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Mashup Score: 0
Concomitant use of 5-aminosalicylic acid did not affect the overall safety and efficacy of IV or subcutaneous vedolizumab in patients with inflammatory bowel disease, according to a post hoc analysis in the Journal of Crohn’s and Colitis. “Professional guidelines recommend 5-ASA therapy as a first-line treatment in mild to moderate ulcerative colitis,” Ryan C. Ungaro, MD, MS,
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Mashup Score: 0Vedolizumab, ustekinumab induce similar rates of clinical response, remission in Crohn’s - 12 month(s) ago
CHICAGO — Biologic-naive patients treated with vedolizumab and ustekinumab for Crohn’s disease had similar rates of clinical response and remission, although mucosal healing and biologic treatment persistence differed at 36 months.“Crohn’s disease is characterized by chronic gastrointestinal inflammation that often requires lifelong treatment,” Marc Ferrante, MD,
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Mashup Score: 0Vedolizumab induces remission in more than 30% of UC patients with chronic pouchitis - 1 year(s) ago
Vedolizumab more effectively induced remission compared with placebo in patients with chronic pouchitis following ileal pouch-anal anastomosis for ulcerative colitis, according to research in The New England Journal of Medicine.“Idiopathic inflammation of the pouch — referred to as pouchitis — is the most common long-term complication of ileal pouch-anal anastomosis (IPAA); it
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Mashup Score: 0Vedolizumab may help prevent lower GI acute GVHD after unrelated stem cell transplant - 1 year(s) ago
Vedolizumab showed greater efficacy than placebo when added to standard prophylaxis for prevention of lower gastrointestinal acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation, according to a study.The initial findings of the GRAPHITE trial, presented at 2023 Tandem Meetings | Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, also showed
Source: www.healio.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Vedolizumab for Ulcerative Colitis Works Best When Given Early - 1 year(s) ago
Benefit confirmed in real-world data
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Mashup Score: 0
CHARLOTTE, N.C. — Exposure to ustekinumab and vedolizumab during pregnancy did not increase maternal and fetal complications, and researchers recommend continued use in pregnant mothers with inflammatory bowel disease. “There is some conflicting data regarding the safety of vedolizumab and ustekinumab in pregnancy,” Rishika Chugh, MD, assistant professor of medicine at the
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Mashup Score: 0
CHARLOTTE, N.C. — Exposure to ustekinumab and vedolizumab during pregnancy did not increase maternal and fetal complications, and researchers recommend continued use in pregnant mothers with inflammatory bowel disease. “There is some conflicting data regarding the safety of vedolizumab and ustekinumab in pregnancy,” Rishika Chugh, MD, assistant professor of medicine at the
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Mashup Score: 0
Older patients with inflammatory bowel disease receiving vedolizumab, particularly those with Crohn’s disease, faced higher risk of treatment failure compared with patients receiving tumor necrosis factor antagonists. The comparative effectiveness study, published in JAMA Network Open, also did not find any significant safety advantage with vedolizumab treatment.
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Mashup Score: 1
Older patients with inflammatory bowel disease receiving vedolizumab, particularly those with Crohn’s disease, faced higher risk of treatment failure compared with patients receiving tumor necrosis factor antagonists. The comparative effectiveness study, published in JAMA Network Open, also did not find any significant safety advantage with vedolizumab treatment.
Source: www.healio.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Tofacitinib May Be More Effective in Anti-TNF-Exposed UC Patients Versus Vedolizumab - 2 year(s) ago
Study may help direct management after a patient fails anti-TNF therapy
Source: www.medpagetoday.comCategories: General Medicine News, Latest HeadlinesTweet
Concomitant 5-ASA treatment does not affect efficacy, safety of #vedolizumab in #IBD @JCC_IBD #GITwitter https://t.co/SYWgJbCZiy