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    Concomitant use of 5-aminosalicylic acid did not affect the overall safety and efficacy of IV or subcutaneous vedolizumab in patients with inflammatory bowel disease, according to a post hoc analysis in the Journal of Crohn’s and Colitis. “Professional guidelines recommend 5-ASA therapy as a first-line treatment in mild to moderate ulcerative colitis,” Ryan C. Ungaro, MD, MS,

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    • Concomitant 5-ASA treatment does not affect efficacy, safety of #vedolizumab in #IBD @JCC_IBD #GITwitter https://t.co/SYWgJbCZiy

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    CHICAGO — Biologic-naive patients treated with vedolizumab and ustekinumab for Crohn’s disease had similar rates of clinical response and remission, although mucosal healing and biologic treatment persistence differed at 36 months.“Crohn’s disease is characterized by chronic gastrointestinal inflammation that often requires lifelong treatment,” Marc Ferrante, MD,

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    • Biologic-naive patients treated with #vedolizumab and #ustekinumab for #Crohns disease had similar rates of clinical response and remission, although mucosal healing and biologic treatment persistence differed at 36 months. #DDW23 @DDWMeeting https://t.co/t0X0mTmTGz

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    Vedolizumab more effectively induced remission compared with placebo in patients with chronic pouchitis following ileal pouch-anal anastomosis for ulcerative colitis, according to research in The New England Journal of Medicine.“Idiopathic inflammation of the pouch — referred to as pouchitis — is the most common long-term complication of ileal pouch-anal anastomosis (IPAA); it

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    • #ICYMI from @NEJM: #Vedolizumab induces remission in more than 30% of #UC patients with chronic #pouchitis #GITwitter #MedTwitter #IBD https://t.co/oFUIcvla3k

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    Vedolizumab showed greater efficacy than placebo when added to standard prophylaxis for prevention of lower gastrointestinal acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation, according to a study.The initial findings of the GRAPHITE trial, presented at 2023 Tandem Meetings | Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, also showed

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    • Vedolizumab may help prevent lower GI acute GVHD after unrelated stem cell transplant. https://t.co/ynRG74OMLe #Vedolizumab #Tandem23 @ASTCT #ASTCT #HemOnc #OncAlert #MedEd

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    CHARLOTTE, N.C. — Exposure to ustekinumab and vedolizumab during pregnancy did not increase maternal and fetal complications, and researchers recommend continued use in pregnant mothers with inflammatory bowel disease. “There is some conflicting data regarding the safety of vedolizumab and ustekinumab in pregnancy,” Rishika Chugh, MD, assistant professor of medicine at the

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    • #ICYMI: @RishikaChughMD reported #ustekinumab, #vedolizumab ‘seem perfectly safe’ during #pregnancy in #IBD patients #GITwitter #MedTwitter https://t.co/WHGbnR4GnG

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    CHARLOTTE, N.C. — Exposure to ustekinumab and vedolizumab during pregnancy did not increase maternal and fetal complications, and researchers recommend continued use in pregnant mothers with inflammatory bowel disease. “There is some conflicting data regarding the safety of vedolizumab and ustekinumab in pregnancy,” Rishika Chugh, MD, assistant professor of medicine at the

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    • Exposure to #ustekinumab and #vedolizumab during pregnancy did not increase maternal and fetal complications, and researchers recommend continued use in pregnant mothers with #IBD @RishikaChughMD #GITwitter #MedTwitter #ACG2022 https://t.co/WHGbnQMx9y

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    Older patients with inflammatory bowel disease receiving vedolizumab, particularly those with Crohn’s disease, faced higher risk of treatment failure compared with patients receiving tumor necrosis factor antagonists. The comparative effectiveness study, published in JAMA Network Open, also did not find any significant safety advantage with vedolizumab treatment.

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    • #ICYMI from @JAMANetworkOpen: Older patients with #IBD at higher risk for treatment failure with #vedolizumab #GITwitter #MedTwitter https://t.co/zujJ0cqgKU

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    Older patients with inflammatory bowel disease receiving vedolizumab, particularly those with Crohn’s disease, faced higher risk of treatment failure compared with patients receiving tumor necrosis factor antagonists. The comparative effectiveness study, published in JAMA Network Open, also did not find any significant safety advantage with vedolizumab treatment.

    Tweet Tweets with this article
    • Older patients with #IBD receiving #vedolizumab, particularly those with #Crohnsdisease, faced higher risk of treatment failure compared with patients receiving tumor necrosis factor antagonists @JAMANetworkOpen #GITwitter #MedTwitter https://t.co/zujJ0cpIVm