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Mashup Score: 5
“A blog about allergy, asthma & immunology”
Source: ivancevichmd.blogspot.comCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 0Omalizumab Drug Survival in Chronic Urticaria: A Retrospective Multicentric French Study - 6 month(s) ago
Omalizumab (OMA) dramatically improves disease control and quality of life in patients with chronic urticaria (CU).
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 1
Patients with chronic spontaneous urticaria (CSU) have spontaneous wheals (W), angioedema (AE), or both, for longer than 6 weeks. Clinical differences between patients with standalone W, standalone AE, and W and AE (W+AE) remain incompletely understood.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 1
The novel therapeutic approach may be promising for patients with the mast cell-dependent disease, which has limited treatment options despite the substantial burden associated with the condition.
Source: www.dermatologytimes.comCategories: Dermatology, Latest HeadlinesTweet
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Mashup Score: 1Most Patients With Autoimmune Chronic Spontaneous Urticaria Also Have Autoallergic Urticaria, but Not Vice Versa - 8 month(s) ago
Two endotypes of chronic spontaneous urticaria (CSU) associated with mast cell–activating autoantibodies are described, namely autoallergic chronic spontaneous urticaria (aaCSU; with immunoglobulin E [IgE]–anti-autoallergens) and autoimmune chronic spontaneous urticaria (aiCSU; with IgG–anti-high-affinity receptor for the Fc region of immunoglobulin E [FcεRI]/IgE).
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 1Association Between Serum Total IgE Levels and Clinical Response to Omalizumab for Chronic Spontaneous Urticaria: A Systematic Review and Meta-Analysis - 8 month(s) ago
Omalizumab is the only biological agent approved for patients with chronic spontaneous urticaria (CSU), but no biomarker is well established for predicting clinical response to omalizumab.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Chronic Spontaneous Urticaria: The Role and Relevance of Autoreactivity, Autoimmunity, and Autoallergy - 8 month(s) ago
Chronic spontaneous urticaria (CSU) is a frequent and often severely disabling disease. A large number of studies were performed during the last 2 decades to clarify its pathogenesis. These studies shed light on the underlying autoimmune mechanisms of CSU pathogenesis and have led us to understand that different mechanisms may exist and, sometimes, coexist behind the same clinical presentation. The present article reviews the meaning of the terms autoreactivity, autoimmunity, and autoallergy, which have been variably used over the years to define different endotypes of the disease.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Managing Chronic Urticaria and Angioedema: Novel Insights - 9 month(s) ago
Chronic urticaria and angioedema are recurrent conditions that significantly impact patients’ quality of life. Over the past 2 decades, extensive research has been conducted to elucidate the underlying mechanisms and improve the management of these conditions. Recent investigations of the pathophysiology of chronic spontaneous urticaria (CSU) have highlighted the role of autoimmune mechanisms, and 2 endotypes have been characterized: type I autoallergic CSU, associated with immunoglobulin E (IgE) antibodies against autoantigens, and type IIb autoimmune CSU, driven by autoantibodies that activate mast cells, including anti- FcεRI (high-affinity receptor for the Fc region of IgE) and anti-IgE.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 4Chronic Urticaria and Angioedema: Masqueraders and Misdiagnoses - 9 month(s) ago
Chronic urticaria is a common condition presenting with intensely pruritic wheals. Although individual lesions resolve within 24 hours, by definition, chronic urticaria lasts for a duration of at least 6 weeks. Both spontaneous and inducible forms exist. In the spontaneous variant, chronic urticaria occurs in the absence of clearly identifiable triggers. In chronic inducible urticaria, specific triggers may include dermatographism, cholinergic (heat), cold, exercise, delayed pressure, and solar.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 3Dupilumab Efficacious in Urticaria Symptom, Quality of Life Improvement - 10 month(s) ago
Over 24 weeks, dupilumab demonstrated efficacy in patients with chronic spontaneous urticaria.
Source: Dermatology TimesCategories: Dermatology, Latest HeadlinesTweet
The effectiveness and safety of a high dose (10 mg) of Desloratadine (Dazit® 10) in treating chronic spontaneous urticaria in India were evaluated in a phase III, multicentric, open-label, single-arm study. Check out the findings here: https://t.co/bmdSnCOsEA #urticaria https://t.co/F81uYq3WXj