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Mashup Score: 6
To our knowledge, this is the largest trial of a tricyclic antidepressant in IBS ever conducted. Titrated low-dose amitriptyline was superior to placebo as a second-line treatment for IBS in primary care across multiple outcomes, and was safe and well tolerated. General practitioners should offer low-dose amitriptyline to patients with IBS whose symptoms do not improve with first-line therapies, with appropriate support to guide patient-led dose titration, such as the self-titration document developed for this trial.
Source: www.thelancet.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 1Diagnosis and Management of Nonalcoholic Fatty Liver Disease - 5 month(s) ago
This JAMA Clinical Guidelines Synopsis summarizes the American Association of Clinical Endocrinology’s 2022 clinical practice guideline for diagnosis and management of nonalcoholic fatty liver disease.
Source: jamanetwork.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 0
All doses of ABX464 significantly improved moderate-to-severe, active ulcerative colitis compared with placebo, as measured by changes in MMS from baseline to week 8. A phase 3 clinical programme is ongoing.
Source: www.thelancet.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0
Focus on fibrosis, inspired by the Review on p633.
Source: www.nature.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 1About The Lancet Gastroenterology & Hepatology - 6 month(s) ago
About
Source: www.thelancet.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0UEG Interview: Jeanin van Hooft - 11 month(s) ago
When I was a trainee, I thought: am I going to be a surgeon or am I going to go into internal medicine? At that stage, we had a doctor…
Source: European Medical JournalCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 2UEG Week 2022 - 1 year(s) ago
Results of the REACT-2 trial, presented by Vipul Jairath (London, ON, Canada) suggest that treating to a target of ulcer healing was no more effective than standard symptom-based management for patients with Crohn’s disease. In this cluster-randomised trial, eligible practices were randomly assigned to an enhanced care algorithm (incorporating early adalimumab and antimetabolite combination…
Categories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0
VIENNA — In a Healio video exclusive, Waqqas Afif, MD, reports results from the phase 3 UNIFI study, in which Stelara safely demonstrated sustained symptomatic and corticosteroid-free remission in adults with ulcerative colitis. According to Afif, 65% of patients who responded to the induction dose of Stelara (ustekinumab, Janssen) were in remission after 44 weeks of maintenance therapy. At
Source: www.healio.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 1
VIENNA — In a Healio video exclusive, Waqqas Afif, MD, reports results from the phase 3 UNIFI study, in which Stelara safely demonstrated sustained symptomatic and corticosteroid-free remission in adults with ulcerative colitis. According to Afif, 65% of patients who responded to the induction dose of Stelara (ustekinumab, Janssen) were in remission after 44 weeks of maintenance therapy. At
Source: www.healio.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 4
In a Healio video exclusive, Simon Travis, DPhil, FRCP, consultant gastroenterologist the University of Oxford, highlighted the unmet need to treat bowel urgency among patients with ulcerative colitis.In online, quantitative, cross-sectional surveys of patients with moderate to severe UC conducted in the United States and Europe, bowel urgency was the second-most frequently reported symptom and
Source: www.healio.comCategories: Gastroenterology, Latest HeadlinesTweet
New online @TheLancet - Amitriptyline at Low-Dose and Titrated for #IBS as Second-Line Treatment in primary care (ATLANTIS): a randomised, double-blind, placebo-controlled, phase 3 trial Catch the #UEGWeek presentation this pm by @alex_ford12399 https://t.co/R0GOVRv3s7