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Mashup Score: 2Long-term safety and outcomes in hereditary tyrosinaemia type 1 with nitisinone treatment: a 15-year non-interventional, multicentre study - 3 year(s) ago
Long-term nitisinone treatment was well tolerated and no new safety signals were revealed. Life-limiting hepatic disease appears to have been prevented by early treatment start. Neonatal screening was the most effective way of ensuring early treatment. Standardised monitoring of blood tyrosine, phenylalanine, and nitisinone levels has potential to guide individualised therapy.
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 0Nitisinone: two decades treating hereditary tyrosinaemia type 1 - 3 year(s) ago
In 1992, Sven Lindstedt and colleagues1 reported the first study using 2-(2-nitro-4-trifluoromethylbenzoyl)-1, 3-cyclohexanedione (nitisinone) to treat five children with hereditary tyrosinaemia type 1. This disorder of tyrosine degradation has a high morbidity and mortality in the early years of life, primarily due to life-threatening hepatic disease including liver failure and hepatocellular…
Categories: Endocrinology, Latest HeadlinesTweet-
Wendy J Introne comments: #Nitisinone: two decades treating #hereditary #tyrosinaemia type 1 https://t.co/jFJDl7BvZd
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Mashup Score: 0Long-term safety and outcomes in hereditary tyrosinaemia type 1 with nitisinone treatment: a 15-year non-interventional, multicentre study - 3 year(s) ago
Long-term nitisinone treatment was well tolerated and no new safety signals were revealed. Life-limiting hepatic disease appears to have been prevented by early treatment start. Neonatal screening was the most effective way of ensuring early treatment. Standardised monitoring of blood tyrosine, phenylalanine, and nitisinone levels has potential to guide individualised therapy.
Categories: Endocrinology, Latest HeadlinesTweet-
In the July Issue: Long-term safety and outcomes in #hereditary #tyrosinaemia type 1 with #nitisinone treatment: a 15-year non-interventional, multicentre study https://t.co/zd7DcYFFqI
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Mashup Score: 2Long-term safety and outcomes in hereditary tyrosinaemia type 1 with nitisinone treatment: a 15-year non-interventional, multicentre study - 3 year(s) ago
Long-term nitisinone treatment was well tolerated and no new safety signals were revealed. Life-limiting hepatic disease appears to have been prevented by early treatment start. Neonatal screening was the most effective way of ensuring early treatment. Standardised monitoring of blood tyrosine, phenylalanine, and nitisinone levels has potential to guide individualised therapy.
Categories: Endocrinology, Latest HeadlinesTweet-
In the July Issue: Long-term safety and outcomes in #hereditary #tyrosinaemia type 1 with #nitisinone treatment: a 15-year non-interventional, multicentre study https://t.co/zd7DcYFFqI
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Mashup Score: 0Nitisinone: two decades treating hereditary tyrosinaemia type 1 - 3 year(s) ago
In 1992, Sven Lindstedt and colleagues1 reported the first study using 2-(2-nitro-4-trifluoromethylbenzoyl)-1, 3-cyclohexanedione (nitisinone) to treat five children with hereditary tyrosinaemia type 1. This disorder of tyrosine degradation has a high morbidity and mortality in the early years of life, primarily due to life-threatening hepatic disease including liver failure and hepatocellular…
Categories: Endocrinology, Latest HeadlinesTweet-
Linked Comment: #Nitisinone: two decades treating #hereditary #tyrosinaemia type 1 https://t.co/jFJDl7BvZd
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Mashup Score: 12The Lancet Diabetes & Endocrinology, July 2021, Volume 9, Issue 7, Pages 407-470, e2 - 3 year(s) ago
Explore the current issue of The Lancet Diabetes & Endocrinology, a monthly journal focussed on diabetes, endocrinology, and metabolism
Source: www.thelancet.comCategories: Endocrinology, Latest HeadlinesTweet-
The July Issue of @TheLancetEndo is now online, featuring #food policies, #BMI and #Ethnicity, #nitisinone for #tyrosinaemia type 1, #cognitive decline in type 1 #diabetes, #COVID19, type 2 diabetes, #PrimaryCare, #Obesity, #publichealth, #China & more https://t.co/02c9tmcEL3 https://t.co/jVIh8Z2AXG
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Mashup Score: 1Long-term safety and outcomes in hereditary tyrosinaemia type 1 with nitisinone treatment: a 15-year non-interventional, multicentre study - 3 year(s) ago
Long-term nitisinone treatment was well tolerated and no new safety signals were revealed. Life-limiting hepatic disease appears to have been prevented by early treatment start. Neonatal screening was the most effective way of ensuring early treatment. Standardised monitoring of blood tyrosine, phenylalanine, and nitisinone levels has potential to guide individualised therapy.
Categories: Endocrinology, Latest HeadlinesTweet-
Online—Long-term safety and outcomes in #hereditary #tyrosinaemia type 1 with #nitisinone treatment: a 15-year non-interventional, multicentre study https://t.co/zd7DcYFFqI #RareDisease
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Mashup Score: 0Nitisinone: two decades treating hereditary tyrosinaemia type 1 - 3 year(s) ago
In 1992, Sven Lindstedt and colleagues1 reported the first study using 2-(2-nitro-4-trifluoromethylbenzoyl)-1, 3-cyclohexanedione (nitisinone) to treat five children with hereditary tyrosinaemia type 1. This disorder of tyrosine degradation has a high morbidity and mortality in the early years of life, primarily due to life-threatening hepatic disease including liver failure and hepatocellular…
Categories: Endocrinology, Latest HeadlinesTweet-
Linked Comment by Wendy J Introne: #Nitisinone: two decades treating #hereditary #tyrosinaemia type 1 https://t.co/jFJDl7BvZd #RareDisease
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Mashup Score: 1Long-term safety and outcomes in hereditary tyrosinaemia type 1 with nitisinone treatment: a 15-year non-interventional, multicentre study - 3 year(s) ago
Long-term nitisinone treatment was well tolerated and no new safety signals were revealed. Life-limiting hepatic disease appears to have been prevented by early treatment start. Neonatal screening was the most effective way of ensuring early treatment. Standardised monitoring of blood tyrosine, phenylalanine, and nitisinone levels has potential to guide individualised therapy.
Categories: Endocrinology, Latest HeadlinesTweet-
Online—Long-term safety and outcomes in #hereditary #tyrosinaemia type 1 with #nitisinone treatment: a 15-year non-interventional, multicentre study https://t.co/zd7DcYFFqI #RareDisease
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Mashup Score: 1Nitisinone: two decades treating hereditary tyrosinaemia type 1 - 3 year(s) ago
In 1992, Sven Lindstedt and colleagues1 reported the first study using 2-(2-nitro-4-trifluoromethylbenzoyl)-1, 3-cyclohexanedione (nitisinone) to treat five children with hereditary tyrosinaemia type 1. This disorder of tyrosine degradation has a high morbidity and mortality in the early years of life, primarily due to life-threatening hepatic disease including liver failure and hepatocellular…
Categories: Endocrinology, Latest HeadlinesTweet-
Wendy J Introne comments on: #Nitisinone: two decades treating #hereditary #tyrosinaemia type 1 https://t.co/jFJDl7BvZd #RareDisease
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Long-term safety and outcomes in #hereditary #tyrosinaemia type 1 with #nitisinone treatment: a 15-year non-interventional, multicentre study https://t.co/zd7DcYFFqI