• Mashup Score: 0

    In contrast to high levels of low-density lipoprotein cholesterol (LDL-C), where reduction invariably results in clinical benefit (irrespective of the therapy/therapies used), the impact of lowerin…

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    • Pegozafermin: An "Entriguing" New Therapy for High Triglycerides https://t.co/GMsSsVsJH9 @PennMedicine @AHAPennsylvania @PennCardiology @VAPhiladelphia @nationallipid @ASPCardio @DLBHATTMD @JohnKastelein @TriglycerideF @readersdigest #triglycerides #NASH @NatureMedicine https://t.co/MK7BV9DT11

  • Mashup Score: 3

    Pegozafermin, a long-acting glycopegylated analog of human fibroblast growth factor 21, is in development for the treatment of severe hypertriglyceridemia (SHTG) and nonalcoholic steatohepatitis. Here we report the results of a phase 2, double-blind, randomized, five-arm trial testing pegozafermin at four different doses (n = 67; 52 male) versus placebo (n = 18; 12 male) for 8 weeks in patients…

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    • Now in @NatureMedicine, ENTRIGUE results which I had presented as a late-breaker at @escardio - profound effects of pegozafermin on several cardiometabolic parameters, including #triglycerides and #liver fat. #cardiotwitter @mmillermd1 Link with images: https://t.co/YTVT0WlvIp

  • Mashup Score: 6
    Our Published Papers - 1 year(s) ago

    Elevated LDL Cholesterol with a Carbohydrate-Restricted Diet: Evidence for a “Lean Mass Hyper-Responder” Phenotype doi.org/10.1093/cdn/nzab144November 30, 2021 Case Report: Hypercholesterolemia “Le…

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    • Quite a lot of folks have pinged me on the recent series on #lipids from @theproof with @Drlipid. Not just for the material they went over, but for some thoughts shared on my own research with regard to #LMHRs, the relevance of ⬆️#HDL & ⬇️#triglycerides, https://t.co/DhO5GJqDyL… https://t.co/xjzckfosSi

  • Mashup Score: 2

    This editorial refers to ‘Elevated remnant cholesterol, plasma triglycerides, and cardiovascular and non-cardiovascular mortality’, by B.N. Wadström et al., htt

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    • Lipoproteins and definitions of ‘remnants: what is relevant for lipid specialists and clinical research with novel therapeutic options on the horizon? https://t.co/TdJUmBsUb6 #cholesterol #triglycerides #remnant #EHJ #cardiotwitter @ESC_Journals @escardio @UKL_Leipzig https://t.co/AXcjAF3qyW