• Mashup Score: 1

    Author links open overlay panel Ankita Agarwal MD, MSc a, Joseph Marion PhD b, Paul Nagy PhD c d, Matthew Robinson MD e, Allan Walkey MD, MSc f, Jonathan Sevransky MD, MHS a • Current challenges to interventional trials and critical care research include an inefficient trial design, heterogenous patient populations, heterogeneous treatment effects, and difficulties with patient enrollment. • Precise phenotyping of critically ill patients may allow more targeted enrollment of patients in critical care

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    • How #Electronic #Medical #Record #Integration Can Support More Efficient #Critical #Care #Clinical #Trials https://t.co/9ATUOEGSif https://t.co/2b8lMHbtMR

  • Mashup Score: 33

    Heart failure (HF) is a leading cause of death and disability in older adults. Despite decades of high-quality evidence to support their use, guidelin…

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    • We review #implementation strategies proven effective in RCTs, recognizing irony that even they havent been widely implemented We propose a #conceptualframework for implementation Even #phase3 trials can follow this framework for early implementation https://t.co/uTc6iJ9VkV 5/ https://t.co/f0rhYOfcI8

    • Implementation trials should be robustly designed #Cluster designs help avoid contamination Trial execution requires alignment - regulatory - public - institution - infrastructure Fidelity should be measured Outcomes should be meaningful https://t.co/uTc6iJ9VkV 4/ https://t.co/vQ6YIbaXgt

    • #ImpSci: study of strategies that ⬆️ systemic uptake of evidence Guided by #conceptualframeworks, implementation research should -be #embedded in health systems -engage the right stakeholders -be tailored to barriers, facilitators, regional context https://t.co/uTc6iJ9VkV 3/ https://t.co/DldyxajmwH

    • There are #barriers to implementation at multiple levels - trial design - healthcare system - intervention - institution - clinician These must be addressed when we plan #implementation or #deimplementation Important processes to consider👇🏽 https://t.co/uTc6iJ9VkV 2/ https://t.co/Bs1pWIcvY8

    • #Implementation lags years behind #evidence How might we design #trials, engage #stakeholders, & align #healthcare systems for better implementation? We offer strategies & propose a conceptual framework to bridge the evidence-care gap @JACCJournals https://t.co/uTc6iJ9VkV 1/ https://t.co/lOEAaSZ4OK

  • Mashup Score: 0

    About ScienceDirectRemote accessShopping cartAdvertiseContact and supportTerms and conditionsPrivacy policyWe use cookies to help provide and enhance our service and tailor content and ads. By continuing you agree to the use of cookies.Copyright © 2023 Elsevier B.V. or its licensors or contributors. ScienceDirect® is a registered trademark of Elsevier B.V.ScienceDirect® is a registered trademark…

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    • Yes- so important to include patients of all races/ethnicities in #clinicaltrials! Honored to be leading this effort for GOG-F. Check out our recent manuscript on improving #IDEA in #trials https://t.co/4ZEOLSX16x @GOG @SGO_org @gyncsm @IGCSociety @acog @AACR @ASCO @AACI_Cancer https://t.co/6Oih3BQ0Ud

  • Mashup Score: 4

    The 3CT Workshop aims to foster an international exchange of ideas where attendees will brainstorm on trial design, conduct, ethics and data interpretation in the critical care area. The sessions will cover domains including drugs, devices, and biomarkers in the field of intensive care. Following the template of the CVCT workshop, the Critical Care Clinical Trialists (3CT) workshop is a…

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    • Register for the #CriticalCare Clinical Trialists program Jun 8-10, DC Attend our sessions on #pragmatic, registry-based #trials, #AI / #digitalhealth & more Multistakeholder discussions w #FDA, #NIH, #researchers, #clinicians #HF #Shock @AlexMebazaa https://t.co/kBgymNN0rn https://t.co/9m0ATF8CrD

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    Dr. Anna Wolska from the Lupus Foundation of America interviews Dr. Andrea Fava from Johns Hopkins University about Belimumab treatment in lupus nephritis. Dr Fava elucidates on the correlation betwee

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    • #Lupus #Science & #Medicine and @LupusOrg Dr. Anna Wolska interviews Dr. Andrea Fava from @JohnHopkinsUni1 about #Belimumab treatment in lupus #nephritis. #SLE #Rheumatology #EULAR2023 #LupusNephritis #Treatment #Biomarker #precisionmedicine #trials https://t.co/w4ZzAavQ8F

  • Mashup Score: 1

    Dr. Anna Wolska from the Lupus Foundation of America interviews Dr. Andrea Fava from Johns Hopkins University about Belimumab treatment in lupus nephritis. Dr Fava elucidates on the correlation betwee

    Tweet Tweets with this article
    • #Lupus #Science & #Medicine and @LupusOrg Dr. Anna Wolska interviews Dr. Andrea Fava from @JohnHopkinsUni1 about #Belimumab treatment in lupus #nephritis. #SLE #Rheumatology #EULAR2023 #LupusNephritis #Treatment #Biomarker #precisionmedicine #trials https://t.co/w4ZzAavQ8F

  • Mashup Score: 1

    Dr. Anna Wolska from the Lupus Foundation of America interviews Dr. Andrea Fava from Johns Hopkins University about Belimumab treatment in lupus nephritis. Dr Fava elucidates on the correlation betwee

    Tweet Tweets with this article
    • #Lupus #Science & #Medicine and @LupusOrg Dr. Anna Wolska interviews Dr. Andrea Fava from @JohnHopkinsUni1 about #Belimumab treatment in lupus #nephritis. #SLE #Rheumatology #EULAR2023 #LupusNephritis #Treatment #Biomarker #precisionmedicine #trials https://t.co/w4ZzAavQ8F