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Mashup Score: 9Study finds new treatment makes patients with life-threatening muscle weakness stronger - 29 day(s) ago
For the thousands of people globally affected by the disease myasthenia gravis (MG), everyday activities become a struggle, and in severe cases, the disease can be life-threatening.
Source: medicalxpress.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 9Add-on dupilumab improves chronic spontaneous urticaria treatment with antihistamines - 5 month(s) ago
ANAHEIM, Calif. — Patients using dupilumab with H1 antihistamines for their chronic spontaneous urticaria experienced greater improvements over 24 weeks than those on antihistamines alone, according to a recent study. “We know that many CSU [chronic spontaneous urticaria] patients are not well-controlled,” Chien-Chia Chuang, PhD, a health economist with Sanofi, said during her
Source: www.healio.comCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 1The emerging role of ctDNA in breast cancer - 6 month(s) ago
Liquid biopsies hold great promise in precision medicine in breast cancer
Source: dailyreporter.esmo.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Relapse Risk and Safety of Long-Term Tocilizumab Use Among Patients With Giant Cell Arteritis: A Single-Enterprise Cohort Study - 6 month(s) ago
Objective To evaluate the safety and efficacy of tocilizumab (TCZ) in giant cell arteritis (GCA) in a large North American cohort. Methods Patients with GCA treated with TCZ between January 1, 2010, and May 15, 2020, were retrospectively identified. Kaplan-Meier methods were used to estimate time to TCZ discontinuation and time to first relapse after TCZ discontinuation. Poisson regression models were used to compare annualized relapse rates before, during, and after TCZ use. Age- and sex-adjusted risk factors associated with relapse on and off TCZ and development of adverse events of significant interest (AESIs) were examined using Cox models. Results One hundred fourteen patients (60.5% female) were included with mean (SD) age 70.4 (8.2) years. Median duration from GCA diagnosis to TCZ start was 4.5 months. Median overall duration of TCZ treatment was 2.3 years. Relapse rate prior to TCZ start (0.84 relapses/person-year) was 3-fold reduced while on TCZ (0.28 relapses/person-year; P <
Source: www.jrheum.orgCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0Fast Acting, Dry Powder, Needle-Free, Intranasal Epinephrine Spray: A Promising Future Treatment for Anaphylaxis - 6 month(s) ago
Epinephrine intramuscular (IM) autoinjector is a life-saving drug for the emergency treatment of immediate-type allergic reactions (type I). Nevertheless, it is sometimes applied incorrectly or underused because of short shelf life, high costs, fear of use, or inconvenience of carrying. FMXIN002, a nasal powder spray of epinephrine, was developed as a needle-free alternative.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Esketamine in Combination with Oral Antidepressant Could Aid Treatment-Resistant Depression - 6 month(s) ago
Individuals treated with esketamine were more likely to reach remission and remain relapse-free at 8 weeks of treatment.
Source: www.pharmacytimes.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 1
Patients with chronic spontaneous urticaria (CSU) have spontaneous wheals (W), angioedema (AE), or both, for longer than 6 weeks. Clinical differences between patients with standalone W, standalone AE, and W and AE (W+AE) remain incompletely understood.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0
Silverberg JI, Guttman-Yassky E, Thaçi D, Irvine AD, Stein Gold L, Blauvelt A, et al. Two phase 3 trials of lebrikizumab for moderate-to-severe atopic dermatitis. N Engl J Med 2023;388:1080-91.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 1Medical news of the North Caucasus :: Scientific journal - 7 month(s) ago
[Original research] [Surgery] Alexandr Muravyev; Ashkhen Shagenovna Galstian; Peter Lavreshin; Sergey Minaev; Roman Juravel; Dmitrii Overchenko; Oleg Lysenko; Oleg Lysenko; Galina Saneeva; Sofia Sergeevna Korablina; Rectovaginal fistulas belong to a rather rare pathology, accounting for about 3 % of all coloproctological diseases and 5 % of all rectal fistulas. This pathology causes significant…
Source: medvestnik.stgmu.ruCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 1Benralizumab treatment of severe asthma in pregnancy: A case series - 7 month(s) ago
Asthma exacerbations, oral corticosteroid use, and increased asthma severity are associated with adverse perinatal outcomes.1 Asthma biologics have transformed the management of severe asthma (SA), but the clinical trials that served as the basis for regulatory approvals for the biologics excluded pregnant women, and data on their safety and efficacy during pregnancy are limited. Here, we present a case series on the use of benralizumab, an IL-5 receptor antagonist, in pregnant women with SA. We obtained informed consent from all patients.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
Study finds new #treatment makes patients with life-threatening muscle weakness stronger @sciencetm https://t.co/9nBISn5P30