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Mashup Score: 1
Clinical Transplantation is an international transplantation journal publishing the latest research surrounding organ and tissue transplant surgery.
Source: onlinelibrary.wiley.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 1Allogeneic haematopoietic stem-cell transplantation versus gene therapy for haemoglobinopathies - 6 month(s) ago
Timothy S Olson
Source: www.thelancet.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Phase III clinical trial of autologous CD34 + cell transplantation to accelerate fracture nonunion repair - BMC Medicine - 6 month(s) ago
Background We previously demonstrated that CD34 + cell transplantation in animals healed intractable fractures via osteogenesis and vasculogenesis; we also demonstrated the safety and efficacy of this cell therapy in an earlier phase I/II clinical trial conducted on seven patients with fracture nonunion. Herein, we present the results of a phase III clinical trial conducted to confirm the results of the previous phase studies using a larger cohort of patients. Methods CD34 + cells were mobilized via administration of granulocyte colony-stimulating factor, harvested using leukapheresis, and isolated using magnetic cell sorting. Autologous CD34 + cells were transplanted in 15 patients with tibia nonunion and 10 patients with femur nonunion, who were followed up for 52 weeks post transplantation. The main outcome was a reduction in time to heal the tibia in nonunion patients compared with that in historical control patients. We calculated the required number of patients as 15 based on the
Source: bmcmedicine.biomedcentral.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 1ASH Clinical News | American Society of Hematology - 7 month(s) ago
An analysis of 994 patients with AML shows that treatment with venetoclax plus low-intensity or intensive chemotherapy attenuates the negative prognostic impact of AML with a splicing factor mutation. Akshat Jain, MD, MPH, a pediatric hematologist at Loma Linda University School of Medicine and Children’s Hospital in California, shares a recent poem of his that was written in tribute to patients with sickle cell disease. A pooled analysis of 11 trials found that half of patients with MM who were treated
Source: ashpublications.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 4Early cessation of calcineurin inhibitors is feasible post–haploidentical blood stem cell transplant: the ANZHIT 1 study - 7 month(s) ago
Key Points. Haplo-HSCT results in encouraging disease-free survival despite significant hemorrhagic cystitis in the MAC arm.Early cessation of CNI is feasible i
Source: ashpublications.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Phase 2 study of PD-1 blockade following autologous transplantation for patients with AML ineligible for allogeneic transplant - 7 month(s) ago
Key Points. Pembrolizumab after autologous transplant is safe and effective, with low nonrelapse mortality and 2-year OS and LFS and OS of 68% and 48%.In patien
Source: ashpublications.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 4The utility of biomarkers in acute GVHD prognostication - 7 month(s) ago
TO THE EDITOR
Source: ashpublications.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Immune profiling after allogeneic hematopoietic cell transplantation in pediatric acute myeloid leukemia - 7 month(s) ago
Key Points. Downregulation of major histocompatibility complex class II expression is observed at posttransplant pediatric AML relapse.Natural killer cells and
Source: ashpublications.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Survival similar in lung transplantation for COVID-19-related ARDS, pulmonary fibrosis - 7 month(s) ago
Patients with COVID-19-related acute respiratory distress syndrome undergoing transplantation had comparable, high survival rates to patients with COVID-19-related pulmonary fibrosis, according to results published in JAMA Surgery.Further, survival rates from these patients did not differ from those of patients who underwent lung transplantation for a non-COVID-19-related reason, according to
Source: www.healio.comCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 3Incidence, clinical presentation, risk factors, outcomes, and biomarkers in de novo late acute GVHD - 7 month(s) ago
Key Points. Compared with classic acute GVHD, late acute GVHD presents with worse clinical severity and higher-risk biomarker parameters.Patients with late acut
Source: ashpublications.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
Includes great graphics detailing immunosuppression complications, post liver transplant metabolic health management, vaccine management and malignancy screening 👇 https://t.co/WgW9vAh2ql #livertwitter https://t.co/DywKpGvylT