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Mashup Score: 11JCI - Epsilon toxin-producing Clostridium perfringens colonize the MS gut and epsilon toxin overcomes immune privilege - 1 year(s) ago
ResearchIn-Press PreviewAutoimmunityMicrobiology Open Access | 10.1172/JCI163239 David Sannino,1 Jennifer R. Linden,1 Sylvia Haigh,1 Baohua Zhao,1 John B. Grigg,2 Paul Zumbo,3 Friederike Dündar,4 Daniel J. Butler,5 Caterina P. Profaci,6 Kiel M. Telesford,1 Paige N. Winokur,7 Kareem R. Rumah,8…
Source: www.jci.orgCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Lead Toxin Concerns Spur Recall of Toddler Sippy Cups - 1 year(s) ago
MONDAY, Nov. 28, 2022 (HealthDay News) — Parents whose toddlers use certain Green Sprouts bottles or cups need to discard them immediately because of a risk of lead exposure, the U.S. Consumer Product Safety Commission (CPSC) warns.When the base of the cups come apart, it exposes a solder dot that …
Source: Consumer Health News | HealthDayCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 183 Americans dead, 1 hospitalized in the Bahamas - 2 year(s) ago
Fox News medical contributor Dr. Marc Siegel weighs in on the causes behind three Americans being found dead inside a resort in the Bahamas.
Source: Fox NewsCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 2
Author summary Mycoplasmas belong to a class of cell-wall deficient bacteria characterized by minimal genomes acquired through regressive evolution. Historically, they were thought to lack many of the common bacterial virulence traits including classical exotoxins and toxin-antitoxin (TA) systems. In this work, we confirmed the presence of different functional TA systems in several isolates of…
Source: journals.plos.orgCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 0
Author summary Mycoplasmas belong to a class of cell-wall deficient bacteria characterized by minimal genomes acquired through regressive evolution. Historically, they were thought to lack many of the common bacterial virulence traits including classical exotoxins and toxin-antitoxin (TA) systems. In this work, we confirmed the presence of different functional TA systems in several isolates of…
Source: journals.plos.orgCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 0Molecular mechanisms of centipede toxin SsTx-4 inhibition of inwardly rectifying potassium channels - 2 year(s) ago
Inwardly rectifying potassium channels (Kirs) are important drug targets, with antagonists for the Kir1.1, Kir4.1, and pancreatic Kir6.2/SUR1 channels being potential drug candidates for treating hypertension, depression, and diabetes, respectively. However, few peptide toxins acting on Kirs are identified and their interacting mechanisms remain largely elusive yet. Herein, we showed that the…
Source: Journal of Biological ChemistryCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 12
While rare, botulism can cause paralysis and is potentially fatal. It is caused by nerve-damaging toxins produced by Clostridium botulinum—the most potent toxins known. These toxins are often found in contaminated food (home canning being a major culprit). Infants can also develop botulism from ingesting C. botulinum spores in honey, soil, or dust; the bacterium then colonizes their intestines…
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0
Tarantula venom is not something people would normally associate with relief from pain, but strangely enough, the ingredients within it could hold the key to new medicines that offer just that, and without some of the common side effects. A new understanding of the way tarantula toxins shut down…
Source: New AtlasCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 9Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins - 4 year(s) ago
A lethal bacterial toxin that plays a major role in toxic shock syndrome uses the host semaphorin proteins as receptors, and structural analysis shows a small binding interface that can be mutated to switch specificity between very different host receptors.
Source: CellCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 9Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins - 4 year(s) ago
A lethal bacterial toxin that plays a major role in toxic shock syndrome uses the host semaphorin proteins as receptors, and structural analysis shows a small binding interface that can be mutated to switch specificity between very different host receptors.
Source: CellCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
Bacterial #toxin may trigger multiple sclerosis onset and relapse @cornell @jclinicalinvest https://t.co/LFVHE7W0P1 https://t.co/XKjejudC3v