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Mashup Score: 12Research team uncovers novel receptor function in fragile X syndrome - 1 month(s) ago
Fragile X syndrome is one of the most commonly inherited forms of autism and intellectual disability, and no treatment currently exists. But a team of University of Illinois researchers led by Vipendra …
Source: medicalxpress.comCategories: General Medicine News, General NewsTweet
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Mashup Score: 11New findings could be life-changing for genetic syndrome sufferers - 2 month(s) ago
An international research team led by QIMR Berghofer and Peter MacCallum Cancer Center has discovered that people with the hereditary cancer disorder Li Fraumeni syndrome are at greater risk of a much …
Source: medicalxpress.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 18
How does coronavirus spread through the body? A new study, available on the preprint server bioRxiv, can help us answer that question. Professor Jakob Nilsson from the Novo Nordisk Center for Protein …
Source: medicalxpress.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0Facial Swelling Secondary to Superior Vena Cava Syndrome - 6 month(s) ago
A 68-year-old woman with a history of stage IIIA ovarian cancer in remission and pulmonary embolism on apixaban presented with recurrent episodic facial and neck swelling and facial flushing for the past 7 months (Figure 1). The patient reported that her symptoms were worse overnight when laying down to sleep and peaked when she woke up in the morning. The swelling improved gradually throughout the day, but never fully resolved. Bending forward exacerbated her facial and neck swelling and flushing.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Lymphocyte transformation test in the diagnosis of adult fish-induced enterocolitis syndrome - 7 month(s) ago
Food protein-induced enterocolitis syndrome (FPIES) is a non–IgE-mediated gastrointestinal food allergy.1 The diagnosis of FPIES is primarily based on the clinical history, although its gastrointestinal symptoms are shared with many other conditions, complicating its differential diagnosis. An oral food challenge is indicated when the diagnosis is unclear, or to determine tolerance, with a potential risk to the patient.2
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 3
Immune checkpoint inhibitors (ICIs) have entailed a radical change in the therapeutic landscape of multiple tumors. The ICIs enhance immunogenic activity against tumor cells through suppression of negative signaling over cytotoxic T cells. Nivolumab is a fully human immunoglobulin G4 antibody that blocks the interaction between programmed cell death protein-1 (PD-1) and its corresponding ligand. Interfering with physiological mechanisms of peripheral immune tolerance conducts intensified systemic immune response, which enhances antitumor activity, but also favors inflammation leading to a wide spectrum of immune-related adverse effects (irAEs).
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Successful revaccination of a child with Gianotti-Crosti syndrome following diphtheria tetanus and rabies vaccinations - 7 month(s) ago
Gianotti-Crosti syndrome (GCS), also known as childhood papular acrodermatitis, is a rare, self-limiting disease characterized by sudden-onset monomorphic papular or papulovesicular eruptions.1-3 It is thought to occur mainly in association with infections and rarely with vaccines.4 The diagnosis is based on clinical signs and symptoms. There are no characteristic laboratory features.2,4 Awareness and clinical suspicion are required to diagnose GCS.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 2Digital Ischemia as a Presenting Feature of Hypereosinophilic Syndrome-Associated Vasculitis - 8 month(s) ago
Hypereosinophilic syndrome (HES) is a disease with diverse clinical presentations including cardiac, neurologic, cutaneous, or pulmonary manifestations.1 We present a case of a 64-year-old man, active smoker, with history of occasional cocaine use who visited the emergency department because of progressive darkening of fingertips for 2 weeks, accompanied by intense pain and aggravated by cold temperature. Physical examination showed ischemia of all fingertips bilaterally, with necrosis of left index, middle, and annular fingers and right middle finger (Figure 1, A), associated with decreased temperature and tenderness to palpation.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Antithyroid arthritis syndrome caused by methimazole in a patient with Graves’ disease - 8 month(s) ago
Summary This is a report on antithyroid arthritis syndrome (AAS) which is a rare adverse effect of antithyroid agents. AAS presents with severe symptoms including myalgia, arthralgia, arthritis, fever, and skin eruption due to the use of antithyroid agents. We encountered a 55-year-old woman with severe pain in the hand and forearm and arthralgia in multiple joints, including the knee, ankle, hand, and wrist on day 23 after initiation of methimazole (MMI) for Graves’ disease. Blood tests revealed elevated inflammation markers such as C-reactive protein and interleukin-6, and magnetic resonance imaging of the hands confirmed inflammation findings. After withdrawing MMI on day 25, symptoms showed a tendency toward improvement. Afterwards, inflammation markers also dropped to an almost normal range. In addition to the above findings, the absence of anti-neutrophil cytoplasmic antibodies and most vasculitis symptoms such as nephritis, skin, or pulmonary lesions led to the diagnosis of AAS.
Source: edm.bioscientifica.comCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 2Wolters Kluwer Health - 9 month(s) ago
JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…
Source: lww.comCategories: Latest Headlines, RheumatologyTweet-
New in PAIN: a systematic review with meta-analysis of stress biomarkers in individuals with #fibromyalgia #syndrome. https://t.co/8f2qXJSk73
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Research team uncovers novel receptor function in fragile X #syndrome @UofIllinois https://t.co/uftCzUtMit