• Mashup Score: 9
    Probiotic supplementation during antibiotic treatment is unjustified in maintaining the gut microbiome diversity: a systematic review and meta-analysis - BMC Medicine - 9 month(s) ago

    Background Probiotics are often used to prevent antibiotic-induced low-diversity dysbiosis, however their effect is not yet sufficiently summarized in this regard. We aimed to investigate the effects of concurrent probiotic supplementation on gut microbiome composition during antibiotic therapy. Methods We performed a systematic review and meta-analysis of randomized controlled trials reporting the differences in gut microbiome diversity between patients on antibiotic therapy with and without concomitant probiotic supplementation. The systematic search was performed in three databases (MEDLINE (via PubMed), Embase, and Cochrane Central Register of Controlled Trials (CENTRAL)) without filters on 15 October 2021. A random-effects model was used to estimate pooled mean differences (MD) with 95% confidence intervals (CI). This review was registered on PROSPERO (CRD42021282983). Results Of 11,769 identified articles, 15 were eligible in the systematic review and 5 in the meta-analyses. Quan

    Source: bmcmedicine.biomedcentral.com
    Categories: General Medicine Journals and Societies, Latest Headlines
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      BMCMedicine

      This systematic review and meta-analysis by Anna Júlia Éliás et al. from the Semmelweis University, Budapest provides new insights into the effect of #probiotic #supplementation during #antibiotic treatment on gut #microbiome diversity - read it here: https://t.co/ZJ7Ijpw3NX https://t.co/viFazoZ9oh

  • Mashup Score: 1
    NAD+ Therapeutics and Skeletal Muscle Adaptation to Exercise in Humans - Sports Medicine - 1 year(s) ago

    Nicotinamide adenine dinucleotide (NAD+) is a vital energy intermediate in skeletal muscle. The discovery of dietary-derived NAD+ precursors has led to the rapid development of NAD+ therapeutics designed to manipulate NAD+ content in target tissues. Of those developed, nicotinamide riboside and nicotinamide mononucleotide have been reported to display health benefit in humans under clinical…

    Source: SpringerLink
    Categories: Latest Headlines, Rheumatology
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      SportsMedicineJ

      NAD+ is a critical coenzyme found in all human cells. Learn how #neutriceutical #supplementation to support NAD+ impacts adaptation to exercise in the review by @campelj_dean and @andyphilp_lab https://t.co/jKgIR7i79p #GSSIXP #OpenAccess https://t.co/5CzQAswr1S

  • Mashup Score: 0
    Cocoa flavanol supplementation reduces risk for cardiovascular death - 2 year(s) ago

    Study participants who were randomly assigned to receive cocoa flavanol supplementation had a 27% lower risk for cardiovascular death than those assigned to placebo, according to data published in The American Journal of Clinical Nutrition.“We see a lot of promise here,” Howard D. Sesso, ScD, MPH, an associate professor in the division of preventive medicine at Brigham and

    Source: www.healio.com
    Categories: General Medicine News, Latest Headlines
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      GoHealio

      Study participants who were randomly assigned to receive #cocoaflavanol #supplementation had a 27% lower risk for #cardiovasculardeath than those assigned to placebo. #flavanols @BrighamWomens https://t.co/40z5mh4gGj

  • Mashup Score: 5
    Vitamin C improves microvascular reactivity and peripheral tissue perfusion in septic shock patients - Critical Care - 2 year(s) ago

    Background Vitamin C has potential protective effects through antioxidant and anti-inflammatory properties. However, the effect of vitamin C supplementation on microvascular function and peripheral tissue perfusion in human sepsis remains unknown. We aimed to determine vitamin C effect on microvascular endothelial dysfunction and peripheral tissue perfusion in septic shock patients. Methods…

    Source: BioMed Central
    Categories: Critical Care, Latest Headlines
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      Crit_Care

      #CritCare #OpenAccess #VitaminC #supplementation improved peripheral #tissue_perfusion and #microvascular reactivity in #septic_shock patients https://t.co/afA5iPj0Iz @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #sepsis #ascorbic_acid #nutrition #infection https://t.co/Xf7aNPryRa