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Mashup Score: 13
Gosh was I lucky to speak with Professor Erik Van Zwet from Leiden University in the Netherlands. He is the first author on a recent NEJM Evidence paper looking at more than 23,000 trials in the Cochrane Database. (I linked to an URL that should get by the paywall.)
Source: www.sensible-med.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 2Data Analysis Techniques for Sedentary Behavior (Pt2) - Data Analysis for SB Mini Series | Physical Activity Researcher - 2 month(s) ago
About the Miniseries: This podcast miniseries, “Data Analysis for Sedentary Behaviour”, hosted by Dr. Olli Tikkanen, aims to deliver a comprehensive understanding of sedentary behavior data analysis. Across six informative episodes, Dr. Tikkanen brings clarity to complex concepts, explores advanced analytic techniques, and introduces software tools that aid in the examination and interpretation of sedentary behavior and physical activity data. This miniseries is designed for a wide audience, from novices in the field to seasoned researchers seeking new insights. About the Episode Topic: In episode two of the series, Dr. Tikkanen dives deep into the key techniques for analyzing sedentary behavior data: descriptive statistics and time series analysis. These approaches represent foundational elements of data analysis, offering researchers powerful tools to better understand and interpret their data. Descriptive statistics, a method used for summarizing and organizing data, offers a prel
Source: paresearcher.podbean.comCategories: General Medicine News, General NewsTweet
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Mashup Score: 0Data Analysis Techniques for Sedentary Behavior (Pt2) - Data Analysis for SB Mini Series | Physical Activity Researcher - 8 month(s) ago
About the Miniseries: This podcast miniseries, “Data Analysis for Sedentary Behaviour”, hosted by Dr. Olli Tikkanen, aims to deliver a comprehensive understanding of sedentary behavior data analysis. Across six informative episodes, Dr. Tikkanen brings clarity to complex concepts, explores advanced analytic techniques, and introduces software tools that aid in the examination and interpretation of sedentary behavior and physical activity data. This miniseries is designed for a wide audience, from novices in the field to seasoned researchers seeking new insights. About the Episode Topic: In episode two of the series, Dr. Tikkanen dives deep into the key techniques for analyzing sedentary behavior data: descriptive statistics and time series analysis. These approaches represent foundational elements of data analysis, offering researchers powerful tools to better understand and interpret their data. Descriptive statistics, a method used for summarizing and organizing data, offers a prel
Source: paresearcher.podbean.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 2Data Analysis Techniques for Sedentary Behavior (Pt2) - Data Analysis for SB Mini Series | Physical Activity Researcher - 8 month(s) ago
About the Miniseries: This podcast miniseries, “Data Analysis for Sedentary Behaviour”, hosted by Dr. Olli Tikkanen, aims to deliver a comprehensive understanding of sedentary behavior data analysis. Across six informative episodes, Dr. Tikkanen brings clarity to complex concepts, explores advanced analytic techniques, and introduces software tools that aid in the examination and interpretation of sedentary behavior and physical activity data. This miniseries is designed for a wide audience, from novices in the field to seasoned researchers seeking new insights. About the Episode Topic: In episode two of the series, Dr. Tikkanen dives deep into the key techniques for analyzing sedentary behavior data: descriptive statistics and time series analysis. These approaches represent foundational elements of data analysis, offering researchers powerful tools to better understand and interpret their data. Descriptive statistics, a method used for summarizing and organizing data, offers a prel
Source: paresearcher.podbean.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 5Timing and Reporting of Secondary Overall Survival End Points for Phase III Trials in Advanced/Metastatic Disease - 8 month(s) ago
Recent therapeutic advances have led to improved patient survival in many cancer settings. Although prolongation of survival remains the ultimate goal of cancer treatment, the availability of effective salvage therapies could make definitive phase III trials with primary overall survival (OS) end points difficult to complete in a timely manner. Therefore, to accelerate development of new therapies, many phase III trials of new cancer therapies are now designed with intermediate primary end points (eg, progression-free survival in the metastatic setting) with OS designated as a secondary end point. We review recently published phase III trials and assess contemporary practices for designing and reporting OS as a secondary end point. We then provide design and reporting recommendations for trials with OS as a secondary end point to safeguard OS data integrity and optimize access to the OS data for patient, clinician, and public-health stakeholders.
Source: ascopubs.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Why estimands are needed to define treatment effects in clinical trials - BMC Medicine - 9 month(s) ago
Background The estimand for a clinical trial is a precise definition of the treatment effect to be estimated. Traditionally, estimates of treatment effects are based on either an ITT analysis or a per-protocol analysis. However, there are important clinical questions which are not addressed by either of these analyses. For example, consider a trial where patients take a rescue medication. The ITT analysis includes data after use of rescue, while the per-protocol analysis excludes these patients altogether. Neither of these analyses addresses the important question of what the treatment effect would have been if patients did not take rescue medication. Main text Trial estimands provide a broader perspective compared to the limitations of ITT and per-protocol analysis. Trial treatment effects depend on how events occurring after treatment initiation such as use of alternative medication or discontinuation of the intervention are included in the definition. These events can be accounted f
Source: bmcmedicine.biomedcentral.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 486Download Statistics And Machine Learning In Python - 9 month(s) ago
In this book we will go back to mathematics and study statistics, and how to calculate important numbers based on data sets. We will also learn how to use various Python modules to get the answers we need.
Source: pyoflife.comCategories: Cardiologists1, Latest HeadlinesTweet
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Mashup Score: 1
Ecological fallacy, defined by Robinson in 1950 as incorrect inferences about individuals based on characteristics and associations observed among groups (1), i
Source: OUP AcademicCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Lack of Treatment Efficacy From Statistically Nonsignificant RCT Results - 10 month(s) ago
This cross-sectional study of statistically nonsignificant results for clinical trial primary outcomes published in leading medical journals in 2021 estimates the strength of support the findings provide for the null vs alternative hypothesis, and reports that many demonstrate conclusive evidence of…
Source: jamanetwork.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 6Cancer Mortality Rates - SEER Cancer Statistics - 12 month(s) ago
Definition and explanation of cancer mortality rate.
Source: SEERCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
Huge thanks to both of you. What a fabulous discussion and comments section. I love learning #statistics and am so proud to host such great content on @Sensible__Med Link here you all https://t.co/W2ztfJKAuk https://t.co/r7yVpGEX0j