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    BACKGROUND: Ca2+ signals in smooth muscle cells (SMCs) contribute to vascular resistance and control blood pressure. Increased vascular resistance in hypertension has been attributed to impaired SMC

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    FootnotesFor Sources of Funding and Disclosures, see page 285.Correspondence to: Oliver Soehnlein, MD, PhD, Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Pettenkoferstr. 9, 80336 Munich. Email oliver.[email protected]comReferences1. Ridker PM, Everett BM, Thuren T, MacFadyen JG, Chang WH, Ballantyne C, Fonseca F, Nicolau J, Koenig W, Anker SD, et al.; CANTOS Trial…

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    • Silvestre-Roig & colleagues report the beneficial effect of #VEGF-C in promoting #atherosclerotic plaque stability by stimulating #cholesterol efflux in arterial #SmoothMuscleCells, diminished #EndoplasmicReticulum stress and prevented cell death. https://t.co/8HmfjgvHjS https://t.co/JNi6oKdQie