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Mashup Score: 1
As much as 43% of patients with systemic sclerosis are malnourished, while 33% demonstrate severe malnutrition, according to data from an Australian study published in Rheumatology. “People living with SSc are at risk for malnutrition from multiple different perspectives,” Jessica L. Fairley, MD, MPH, of the department of rheumatology at St. Vincent’s Hospital in Melbourne,
Source: www.healio.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 3
Patients with higher levels of gamma-glutamyl transferase, and particularly men, demonstrate a significantly higher risk for systemic sclerosis, according to data published in Nature Scientific Reports. “Early detection of SSc and timely implementation of treatment are important for better outcomes,” Oh Chan Kwon, MD, of Yonsei University College of Medicine, in Seoul, South Korea,
Source: www.healio.comCategories: General Medicine News, RheumatologyTweet-
Elevated gamma-glutamyl transferase levels were associated with significantly increased systemic #sclerosis risk, especially in men. 🔗Read more about the new study in Nature Scientific Reports: https://t.co/9lDZIrRSeR
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Mashup Score: 4Association Between Diseases and Symptoms Diagnosed in Primary Care and the Subsequent Specific Risk of Multiple Sclerosis - 5 month(s) ago
Objective: Previous studies have reported a possible prodrome in multiple sclerosis (MS) defined by non-specific symptoms including mood disorder or genito-urinary symptoms and increased health care use detected several years before diagnosis. This study aimed to evaluate agnostically the associations between diseases and symptoms diagnosed in primary care and the risk of multiple sclerosis (MS) relative to controls and two other autoimmune inflammatory diseases with similar population characteristics, namely lupus and Crohn’s disease. Methods: A case-control study was conducted using electronic health records from the Health Improvement Network database in the UK and France. We agnostically assessed the associations between 113 diseases and symptoms in the five years before and after diagnosis in patients with subsequent diagnosis of MS. Individuals with a diagnosis of MS were compared to individuals without MS, and individuals with two other auto-immune diseases, Crohn’s disease and
Source: n.neurology.orgCategories: General Medicine News, General HCPsTweet-
Multiple #sclerosis: New study highlights five warning signs of the disease @InstitutCerveau https://t.co/u9fzAyzMv1 https://t.co/6EDECxoBJT
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Mashup Score: 0Cataracts and Russian-Style Radial Keratotomy - 8 month(s) ago
A patient presents with nuclear sclerosis, fluctuating vision, and a history of eight-incision centripetal radial keratotomy.
Source: crstoday.comCategories: Latest Headlines, OphthalmologyTweet-
A patient presents with nuclear #sclerosis, fluctuating vision, and a history of eight-incision centripetal radial #keratotomy. Read the case: https://t.co/AUIey3n5fC https://t.co/q8XG1W5AHy
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Mashup Score: 0Tripterygium wilfordii derivative celastrol, a YAP inhibitor, has antifibrotic effects in systemic sclerosis - 10 month(s) ago
Objectives Systemic sclerosis (SSc) is characterised by extensive tissue fibrosis maintained by mechanotranductive/proadhesive signalling. Drugs targeting this pathway are therefore of likely therapeutic benefit. The mechanosensitive transcriptional co-activator, yes activated protein-1 (YAP1), is activated in SSc fibroblasts. The terpenoid celastrol is a YAP1 inhibitor; however, if celastrol can…
Source: Annals of the Rheumatic DiseasesCategories: Latest Headlines, RheumatologyTweet-
What is new on the treatment of #systemic #sclerosis? ▶️ celastrol impairs fibrotic phenotype of fibroblasts ▶️ celastrol counteracts bleomycin-induced gene expression programmes ▶️ celastrol antagonise the mechanosensitive YAP pathway 🔗 https://t.co/y499g49s6W
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Mashup Score: 0Obstructive sleep apnea negatively affects cognition in women with multiple sclerosis - 12 month(s) ago
Obstructive sleep apnea had a significant effect on perceived problems with cognitive function in women with multiple sclerosis, according to study results published in Multiple Sclerosis Journal.“Our findings provide new evidence to suggest that sleep disorders may play a pivotal role in the development of cognitive problems in women with multiple sclerosis [MS],” Tiffany J. Braley,
Source: www.healio.comCategories: Latest Headlines, PulmonologyTweet-
Published in @MSJ_Research: Obstructive sleep apnea (#OSA) had a significant effect on perceived problems with #cognitive function in women with multiple #sclerosis. @healiowomen @healioneurology https://t.co/lXgF4zTtfp
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Mashup Score: 0
For diagnosing systemic sclerosis-related ILD, Krebs von den Lungen-6, surfactant protein-D and interleukin-8 in blood/bronchoalveolar lavage fluid samples were found to be “reliable biomarkers,” according to results published in Thorax.“Systemic sclerosis (SSc) is a rare but severe auto-immune disease that is poorly understood,” Bettina C. Schock, PhD, lecturer at The
Source: www.healio.comCategories: Latest Headlines, PulmonologyTweet-
Published in @ThoraxBMJ: For diagnosing systemic #sclerosis-related #ILD, Krebs von den Lungen-6, surfactant protein-D and interleukin-8 in blood/bronchoalveolar lavage fluid samples were found to be “reliable biomarkers.” @HealioRheum https://t.co/b8gBkFQx2F
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Mashup Score: 1Composite serum biomarker may improve identification of interstitial lung disease in SSc - 1 year(s) ago
A composite biomarker index could improve the risk stratification and diagnosis of interstitial lung disease in patients with systemic sclerosis, according to data published in Arthritis & Rheumatology. “ILD is detectable in up to 80% of patients with systemic sclerosis (SSc), and a leading cause of morbidity and mortality,” Adelle S. Jee, PhD, of the department of respiratory
Source: www.healio.comCategories: Latest Headlines, RheumatologyTweet-
ICYMI: A composite biomarker index could improve the #risk stratification and diagnosis of interstitial lung disease in patients with systemic #sclerosis @rpahos_school #RheumTwitter https://t.co/aT6g2lb1bg
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Mashup Score: 0Composite serum biomarker may improve identification of interstitial lung disease in SSc - 1 year(s) ago
A composite biomarker index could improve the risk stratification and diagnosis of interstitial lung disease in patients with systemic sclerosis, according to data published in Arthritis & Rheumatology. “ILD is detectable in up to 80% of patients with systemic sclerosis (SSc), and a leading cause of morbidity and mortality,” Adelle S. Jee, PhD, of the department of respiratory
Source: www.healio.comCategories: Latest Headlines, RheumatologyTweet-
A composite biomarker index could improve the #risk stratification and diagnosis of interstitial lung disease in patients with systemic #sclerosis @rpahos_school #RheumTwitter https://t.co/aT6g2lb1bg
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Mashup Score: 1Recent systemic sclerosis-related pulmonary hypertension patients show better survival - 1 year(s) ago
Patients diagnosed with systemic sclerosis-related pulmonary hypertension in the last 10 years had better survival than those diagnosed prior, according to results published in American Journal of Respiratory and Critical Care Medicine.“We believe that with combined therapy, patients with systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) may have much better response
Source: www.healio.comCategories: Latest Headlines, PulmonologyTweet-
“The future for pulmonary arterial hypertension, and particularly systemic #sclerosis-associated #PAH is upfront combination (dual or triple) therapy,” Paul M. Hassoun, MD, at @HopkinsMedicine, told Healio. https://t.co/g1cS4Y4l9y
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🥪As much as 43% of patients with systemic #sclerosis are malnourished -- 33% severely so, according to a new study Check Healio for more info, with input from lead author Dr. Jessica Fairley of @StVincentsMelb ⬇️ https://t.co/NfV6hu5OAr