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Mashup Score: 8Improving representativeness in trials: a call to action from the Global Cardiovascular Clinical Trialists Forum - 2 month(s) ago
Abstract. Participants enrolled in cardiovascular disease (CVD) randomized controlled trials are not often representative of the population living with the dise
Source: academic.oup.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 9
Collapse all Expand all Background Researchers and decision‐makers often use evidence from randomised controlled trials (RCTs) to determine the efficacy or effectiveness of a treatment or intervention. Studies with observational designs are often used to measure the effectiveness of an intervention in ‘real world’ scenarios. Numerous study designs and their modifications (including both…
Source: www.cochranelibrary.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 5Search | Cochrane Library - 4 month(s) ago
Our site uses cookies to improve your experience. You can find out more about our use of cookies in About Cookies, including instructions on how to turn off cookies if you wish to do so. By continuing to browse this site you agree to us using cookies as described in About Cookies. Trusted evidence. Informed decisions. Better health. W Xinmin, Y Wenkai, S Yahui, L Fei Chinese journal of tissue engi neering research, 2024, 28(3), 404‐410 | added to CENTRAL: Mon Jul 31 00:00:00 GMT 2023 | 2023 Issue 7
Source: www.cochranelibrary.comCategories: General Medicine News, General NewsTweet
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Mashup Score: 5Search | Cochrane Library - 5 month(s) ago
Our site uses cookies to improve your experience. You can find out more about our use of cookies in About Cookies, including instructions on how to turn off cookies if you wish to do so. By continuing to browse this site you agree to us using cookies as described in About Cookies. Trusted evidence. Informed decisions. Better health. W Xinmin, Y Wenkai, S Yahui, L Fei Chinese journal of tissue engi neering research, 2024, 28(3), 404‐410 | added to CENTRAL: Mon Jul 31 00:00:00 GMT 2023 | 2023 Issue 7
Source: www.cochranelibrary.comCategories: General Medicine News, General NewsTweet
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Mashup Score: 0Search | Cochrane Library - 6 month(s) ago
Our site uses cookies to improve your experience. You can find out more about our use of cookies in About Cookies, including instructions on how to turn off cookies if you wish to do so. By continuing to browse this site you agree to us using cookies as described in About Cookies. Trusted evidence. Informed decisions. Better health. W Xinmin, Y Wenkai, S Yahui, L Fei Chinese journal of tissue engi neering research, 2024, 28(3), 404‐410 | added to CENTRAL: Mon Jul 31 00:00:00 GMT 2023 | 2023 Issue 7
Source: www.cochranelibrary.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0
Objectives We assessed the feasibility of an appropriately powered randomised trial by evaluating whether participants could be recruited and retained, and sought preliminary information on exclusive breastfeeding rates. Setting Primary healthcare facility, serving a rural community. Participants Women initiating breast feeding within 24 hours of giving birth, on antiretroviral treatment and aged ≥18 years. Interventions We randomised mother–infant pairs to receive weekly text messaging encouraging exclusive breast feeding plus in-person individual motivational interviews post partum at weeks 2, 6 and 10, or standard infant feeding counselling. Outcome measures The feasibility endpoints included number of participants who consented to participate and number with complete evaluation of infant feeding practices at study visits. Exploratory endpoints included number of participants who exclusively breast fed at 24 weeks post partum and number of participants adhering to study protocol. Re
Source: bmjopen.bmj.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 8
Four weeks versus six weeks of immobilization in a cast following closed reduction for displaced distal radial fractures in adult patients: a multicentre randomized controlled trial
Source: boneandjoint.org.ukCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0
October 10, 2023 — Elixir Medical, a developer of innovative cardiovascular technologies, announced it will present primary endpoint and 6-month data from its DESyne BDS Plus Randomized Clinical Trial (RCT), a prospective, multicenter, single-blind study, as part of The Innovation Program at the Transcatheter Cardiovascular Therapeutics (TCT) conference in San Francisco. The data compare DESyne BDS Plus, the world’s first triple drug-eluting stent with local anticoagulation delivery technology using two anticoagulants (rivaroxaban and argatroban) and an anti-proliferative mTOR inhibitor (sirolimus) to a second-generation durable polymer DES. “Stent thrombosis after percutaneous coronary intervention (PCI), though rare, is a severe complication with death or heart attack risk of up to 50% after the event. Dual antiplatelet therapy (DAPT) has played an integral role in keeping stent thrombosis rates low, but requires patient compliance for a minimum of six months and is associated with a
Source: www.dicardiology.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 3Prebiotic diet changes neural correlates of food decision-making in overweight adults: a randomised controlled within-subject cross-over trial - 7 month(s) ago
Objective Animal studies suggest that prebiotic, plant-derived nutrients could improve homoeostatic and hedonic brain functions through improvements in microbiome–gut–brain communication. However, little is known if these results are applicable to humans. Therefore, we tested the effects of high-dosed prebiotic fibre on reward-related food decision-making in a randomised controlled within-subject cross-over study and assayed potential microbial and metabolic markers. Design 59 overweight young adults (19 females, 18–42 years, body mass index 25–30 kg/m2) underwent functional task MRI before and after 14 days of supplementary intake of 30 g/day of inulin (prebiotics) and equicaloric placebo, respectively. Short chain fatty acids (SCFA), gastrointestinal hormones, glucose/lipid and inflammatory markers were assayed in fasting blood. Gut microbiota and SCFA were measured in stool. Results Compared with placebo, participants showed decreased brain activation towards high-caloric wanted foo
Source: gut.bmj.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 1
BACKGROUND: We examined whether the primary composite outcome (cardiovascular death or heart failure hospitalization) was related to differences in background use and dosing of guideline-directed med
Source: www.ahajournals.orgCategories: Cardiology News and Journals, Latest HeadlinesTweet
Barriers 🔹ExclusionCriteria (often unjustified in context of the #RCT) 🔹need for consent from👨🏻🦱 🔹concern re no fetal consent (does fetus consent to evidence-devoid clinical care?) 🔹culture that accepts evidence gaps in Tx of🤰🏻 More to come.. https://t.co/GaLMS5pAfN https://t.co/wZ4LgodUsX