• Mashup Score: 6

    While germline and somatic mutations in the gene PTPN11, encoding a phosphatase which regulates the RAS signaling pathway, are well characterized in children with Noonan syndrome and juvenile myelomonocytic leukemia, less is known about their clinical impact in adults with acute myeloid leukemia (AML). To elucidate the effect of PTPN11 mutations (PTPN11mut) on clinical outcomes, we screened adult…

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    • The Clinical impact of #PTPN11 mutations in adults w/acute myeloid leukemia | Leukemia ⁦⁦@Malfayez7⁩ ⁦@GhayasIssa⁩ ⁦@TapKadia⁩ ⁦@garciamanero⁩ ⁦@DrHKantarjian⁩ ⁦@GCC_Cortes⁩ @doctorpemm⁩ ⁦@GBorthakur⁩ #leusm https://t.co/XjSGdRflfA

  • Mashup Score: 2

    While germline and somatic mutations in the gene PTPN11, encoding a phosphatase which regulates the RAS signaling pathway, are well characterized in children with Noonan syndrome and juvenile myelomonocytic leukemia, less is known about their clinical impact in adults with acute myeloid leukemia (AML). To elucidate the effect of PTPN11 mutations (PTPN11mut) on clinical outcomes, we screened adult…

    Tweet Tweets with this article
    • The Clinical impact of #PTPN11 mutations in adults with acute myeloid leukemia | Leukemia ⁦@Malfayez7⁩ ⁦@GBorthakur⁩ ⁦@LeukemiaMDA⁩ #leusm #endcancer https://t.co/XjSGdRflfA

  • Mashup Score: 7

    While germline and somatic mutations in the gene PTPN11, encoding a phosphatase which regulates the RAS signaling pathway, are well characterized in children with Noonan syndrome and juvenile myelomonocytic leukemia, less is known about their clinical impact in adults with acute myeloid leukemia (AML). To elucidate the effect of PTPN11 mutations (PTPN11mut) on clinical outcomes, we screened adult…

    Tweet Tweets with this article
    • 👉👉👉The Clinical impact of #PTPN11 mutations in adults with acute myeloid leukemia | Leukemia || ⁦@LeukemiaMDA⁩ ⁦@MDAndersonNews⁩ #endcancer #leusm #mpnsm #MDSsm https://t.co/XjSGdRflfA

  • Mashup Score: 1

    While germline and somatic mutations in the gene PTPN11, encoding a phosphatase which regulates the RAS signaling pathway, are well characterized in children with Noonan syndrome and juvenile myelomonocytic leukemia, less is known about their clinical impact in adults with acute myeloid leukemia (AML). To elucidate the effect of PTPN11 mutations (PTPN11mut) on clinical outcomes, we screened adult…

    Tweet Tweets with this article
    • 👉👉👉Our group’s new report led by ⁦@Malfayez7⁩ & ⁦@GBorthakur⁩ Clinical impact of #PTPN11 mutations in AML ⁦@NicholasShortMD⁩ ⁦@GCC_Cortes⁩ ⁦@RitaAssi4⁩ ⁦@garciamanero⁩ ⁦⁩ ⁦@Daver_Leukemia⁩⁩ ⁦#leusm https://t.co/XjSGdRflfA

  • Mashup Score: 6

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    • Germline RASopathy syndromes and monocytosis| Spontaneous reversions| @LashoTerra #Noonansyndrome #RAS |#CBL #PTPN11 |Similarities with pCMML|https://t.co/YbqCP1iFec

  • Mashup Score: 0

    Histiocytic sarcoma (HS) is a rare, aggressive, and heterogeneous cancer, which remains hard to treat. Here, the authors compare genetic alterations between human HS and spontaneously occurring canin…

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    • NOW ONLINE Read the new article by Benoit Hédan et al. ➡️https://t.co/J1o1HHBpkp | PTPN11 mutations in canine and human disseminated histiocytic sarcoma | #histiocyticsarcoma #dog #PTPN11 @UnivRennes1 @IGDRennes @HitteChristophe https://t.co/oWv9UaYK8x