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    In The Lancet Diabetes & Endocrinology, Petr Ostadal and colleagues report a post-hoc subgroup analysis of the ODYSSEY OUTCOMES trial assessing the contribution of metabolic risk factors to future cardiovascular events in patients with recent acute coronary syndrome.1 This large cardiovascular outcome trial, describes the benefits of additional LDL cholesterol reduction with the PCSK9 inhibitor…

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    • Traci A Turner & Evan A Stein comment: Targeting #PCSK9 inhibitors to those who will benefit most https://t.co/5plRd3SdPg #alirocumab #ACS #cardiovascular #ODYSSEY OUTCOMES

  • Mashup Score: 1

    In The Lancet Diabetes & Endocrinology, Petr Ostadal and colleagues report a post-hoc subgroup analysis of the ODYSSEY OUTCOMES trial assessing the contribution of metabolic risk factors to future cardiovascular events in patients with recent acute coronary syndrome.1 This large cardiovascular outcome trial, describes the benefits of additional LDL cholesterol reduction with the PCSK9 inhibitor…

    Tweet Tweets with this article
    • Traci A Turner & Evan A Stein comment on: Targeting #PCSK9 inhibitors to those who will benefit most https://t.co/5plRd3SdPg #alirocumab #ODYSSEY OUTCOMES https://t.co/6YHHA47OIc

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    New data from the ODYSSEY Outcomes trial show that alirocumab is effective at reducing risk for any stroke without increasing risk for hemorrhagic stroke.In a cohort of 18,924 patients with recent ACS and elevated LDL despite intensive statin therapy, alirocumab (Praluent, Sanofi/Regeneron) was effective in reducing the risk for any stroke (HR = 0.72; 95% CI, 0.57-0.91) and ischemic stroke (HR =

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    • Findings from the #ODYSSEY outcomes trial showed that #alirocumab may reduce #stroke risk without increasing odds of #hemorrhage, according to research published in @CircAHA #AHAJournals @American_Heart https://t.co/Jk5kYotutm