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Mashup Score: 4Wolters Kluwer Health - 10 month(s) ago
JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…
Source: lww.comCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 0Ocrelizumab Achieved Pregnancy Safety and Reduced Disease Progression for Relapsing-Remitting Multiple Sclerosis - Practical Neurology - 2 year(s) ago
In phase 3b of the ENSEMBLE study (NCT03085810), participants treated with ocrelizumab (Ocrevus; Genentech, South San Francisco, CA) for early-stage r
Source: Practical NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 0
Collapse all Expand all Background Ocrelizumab is a humanised anti‐CD20 monoclonal antibody developed for the treatment of multiple sclerosis (MS). It was approved by the Food and Drug Administration (FDA) in March 2017 for using in adults with relapsing‐remitting multiple sclerosis (RRMS) and primary progressive multiple sclerosis (PPMS). Ocrelizumab is the only…
Source: www.cochranelibrary.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 0
Presenting at CMSC 2022, researchers evaluated the decline in the anti-JCV antibody index in patients with MS through 2 years of ocrelizumab treatment.
Source: Neurology AdvisorCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 0
Presenting at CMSC 2022, researchers evaluated the response to the mRNA-1273 vaccine in patients who received DMTs for MS.
Source: Neurology AdvisorCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 0
Collapse all Expand all Background Ocrelizumab is a humanised anti‐CD20 monoclonal antibody developed for the treatment of multiple sclerosis (MS). It was approved by the Food and Drug Administration (FDA) in March 2017 for using in adults with relapsing‐remitting multiple sclerosis (RRMS) and primary progressive multiple sclerosis (PPMS). Ocrelizumab is the only…
Source: www.cochranelibrary.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0B-cell therapies, mycophenolate worsen COVID-19 vaccine response in inflammatory disease - 2 year(s) ago
Patients with chronic inflammatory disease on immunosuppressants, especially B-cell depleting agents, mycophenolate and glucocorticoids, exhibited poor antibody responses to the mRNA vaccine for COVID-19, according to a presenter here.“It is well established that patients with various autoimmune diseases who are on immunosuppression are at increased risk for severe manifestations of
Source: www.healio.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 11Safety of Ocrelizumab in Patients With Relapsing and Primary Progressive Multiple Sclerosis - 3 year(s) ago
Background and Objectives To report safety of ocrelizumab (OCR) up to 7 years in patients with relapsing multiple sclerosis (RMS) and primary progressive multiple sclerosis (PPMS) enrolled in clinical trials or treated in real-world postmarketing settings. Methods Safety analyses are based on integrated clinical and laboratory data for all patients who received OCR in 11 clinical trials,…
Source: NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 1Study identifies predictors of COVID-19 vaccine response in rituximab-treated patients - 3 year(s) ago
Among people treated with anti-CD20 B cell-depleting agents, timing of treatment and numbers of circulating CD4+ and CD19+ cells are significant predictors of immune responses to messenger (m)RNA vaccines against SARS-CoV-2, shows the RituxiVac study.
Source: rheumatology.medicinematters.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 1
Objective To evaluate the clinical consequences of extended interval dosing (EID) of ocrelizumab in relapsing-remitting multiple sclerosis (RRMS) during the coronavirus disease 2019 (COVID-19) pandemic. Methods In our retrospective, multicenter cohort study, we compared patients with RRMS on EID (defined as ≥4-week delay of dose interval) with a control group on standard interval dosing (SID) at…
Categories: Latest Headlines, NeurologyTweet
Via @JAMANeuro: #Ocrelizumab seems to be more effective than dimethyl fumarate or fingolimod for keeping relapsing-remitting #MultipleSclerosis in check when switching from natalizumab: https://t.co/Rut5GNXOP5 #neurotwitter #MS @AANMember https://t.co/11RnA8cTL7