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Mashup Score: 0A spatially resolved atlas of the human lung characterizes a gland-associated immune niche - PubMed - 1 year(s) ago
Single-cell transcriptomics has allowed unprecedented resolution of cell types/states in the human lung, but their spatial context is less well defined. To (re)define tissue architecture of lung and airways, we profiled five proximal-to-distal locations of healthy human lungs in depth using multi-om …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0Sentinel p16INK4a+ cells in the basement membrane form a reparative niche in the lung - PubMed - 2 year(s) ago
We engineered an ultrasensitive reporter of p16INK4a, a biomarker of cellular senescence. Our reporter detected p16INK4a-expressing fibroblasts with certain senescent characteristics that appeared shortly after birth in the basement membrane adjacent to epithelial …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet-
#Sentinel #p16INK4a+ cells in the basement membrane form a #reparative #niche in the #lung https://t.co/wKdBa9OTMQ https://t.co/GARIbXtqWg
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Mashup Score: 1Intersection of Inflammation and Senescence in the Aging Lung Stem Cell Niche - PubMed - 2 year(s) ago
Aging is the final stage of development with stereotyped changes in tissue morphology. These age-related changes are risk factors for a multitude of chronic lung diseases, transcending the diverse pathogenic mechanisms that have been studied in disease-specific contexts. Two of the hallmarks of agin …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet-
Intersection of #Inflammation and #Senescence in the #Aging #Lung #Stem #Cell #Niche https://t.co/3Br1Jb8JFH https://t.co/uprWVEYav5
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Mashup Score: 0Hallmarks of Cancer: New Dimensions - 2 year(s) ago
The hallmarks of cancer conceptualization is a heuristic tool for distilling the vast complexity of cancer phenotypes and genotypes into a provisional set of underlying principles. As knowledge of cancer mechanisms has progressed, other facets of the disease have emerged as potential refinements. Herein, the prospect is raised that phenotypic plasticity and disrupted differentiation is a discrete…
Source: Cancer DiscoveryCategories: Hem/Oncs, Latest HeadlinesTweet-
Happy to see this out with #TME #cell plasticity, #microbiome and other regulators of #niche microenvironments getting duly recognized https://t.co/1T3cHuoaCg
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Mashup Score: 1
When I first saw a 3D printed drug, it was something out of a science fiction movie. I was blown away by it. But it is not just a futuristic concept …
Source: www.linkedin.comCategories: Healthcare Professionals, Latest HeadlinesTweet-
I think, we shouldn't see #3D #printed #medicine as the holy grail, that will change everything, but rather a brilliant solution for a #niche field. @FabRx_3DP goes as far as to say that there is no drug type posing them an invincible barrier. 👉https://t.co/ql1WbyDW8X
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A spatially resolved atlas of the #human #lung characterizes a #gland- #associated #immune #niche https://t.co/8EyPa7mXS8 https://t.co/62nxD30VNf