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    In this study, we demonstrated an essential function of the hexosamine biosynthesis pathway (HBP)–associated O -linked β- N -acetylglucosamine ( O -GlcNAc) signaling in influenza A virus (IAV)–induced cytokine storm. O -GlcNAc transferase (OGT), a key enzyme for protein O -GlcNAcylation, mediated IAV-induced cytokine production. Upon investigating the mechanisms driving this event, we determined…

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