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    Background Spermatogenic impairments can lead to male infertility by different pathological conditions, such as multiple morphological abnormalities of the sperm flagella (MMAF) and non-obstructive azoospermia (NOA). Genetic factors are involved in impaired spermatogenesis. Methods and results Here, we performed genetic analyses through whole-exome sequencing in a cohort of 334 Han Chinese…

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    • Biallelic mutations in CFAP54 cause #MaleInfertility with severe morphological abnormalities of the sperm flagella (MMAF) and non-obstructive azoospermia (NOA) ➡️ https://t.co/2sLBtAHIX8 #Infertility #Genetics #Genomics Pic: Noun Proj - LucasHelle https://t.co/sEPawku5hI

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    Infertility is defined by the inability of a sexually active, non-contraceptive couple to achieve spontaneous pregnancy within 1 year.

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    • Inform men with Yq microdeletion and their partners who wish to proceed with intracytoplasmic sperm injection (ICSI) that microdeletions will be passed to sons, but not to daughters. #maleinfertility #eauguidelines https://t.co/YvHff5yg9E

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    “When you’re talking about ‘impact,’ I don’t think it gets any bigger than treating male infertility, because you’re surgically treating the man, of course, but you’re really treating the couple as a whole, and you’re helping potentially create a new life,” says Justin Dubin, MD.

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    • Urology Times 50 Innovations Series: Treatments for male infertility https://t.co/0lAXjwvj5D #urology #urologist #menshealth #Uro50 #maleinfertility @justindubinmd @NM_Urology