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Mashup Score: 3
BACKGROUND: Efferocytosis is an activity of macrophages that is pivotal for the resolution of inflammation in hypertension. The precise mechanism by which macrophages coordinate efferocytosis and int
Source: www.ahajournals.orgCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 0New Insights Into The Anti-Aging Properties Of Klotho - 9 month(s) ago
The Klotho gene has gained increasing attention for its anti-aging properties. A new study finds that the benefits of this circulating hormone extend beyond the brain.
Source: www.forbes.comCategories: Healthcare Professionals, Latest HeadlinesTweet-
NB: New Insights Into The Anti-#Aging Properties Of #Klotho @WmHaseltine https://t.co/LKWtNgCiNt #inflammation #macrophage #learning #cognition https://t.co/YeZlYYGEXx
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Mashup Score: 1
BACKGROUND: The mTOR (mechanistic target of rapamycin) pathway is a complex signaling cascade that regulates cellular growth, proliferation, metabolism, and survival. Although activation of mTOR sign
Source: www.ahajournals.orgCategories: Cardiology News and Journals, Latest HeadlinesTweet-
Zhang et al reveal the atheroprotective role of #macrophage #mTORC2 signaling via #FoxO1-mediated stimulation of #IL1β transcription. Learn about its role in #atherosclerosis at https://t.co/Lxx0MeDu21 @XiangyuZ0321 @RazaniLab @Art_Yurdagul @Astrid_C_RV @tdevans27 https://t.co/mQFO7g4G4W
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Mashup Score: 3Macrophage phagocytosis of SARS-CoV-2-infected cells mediates potent plasmacytoid dendritic cell activation - Cellular & Molecular Immunology - 11 month(s) ago
Early and strong interferon type I (IFN-I) responses are usually associated with mild COVID-19 disease, whereas persistent or unregulated proinflammatory cytokine responses are associated with severe disease outcomes. Previous work suggested that monocyte-derived macrophages (MDMs) are resistant and unresponsive to SARS-CoV-2 infection. Here, we demonstrate that upon phagocytosis of…
Source: NatureCategories: Infectious Disease, Latest HeadlinesTweet-
Scientists at @ivi_switzerland describe a novel and potent pathway of plasmacytoid #DendriticCell activation 🔛 that is linked to the #macrophage-mediated clearance of #SARSCoV2 infected cells. #OpenAccess: 📖 https://t.co/e4qTyenFL4 https://t.co/zXtw3eB0fF
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Mashup Score: 7Macrophage phagocytosis of SARS-CoV-2-infected cells mediates potent plasmacytoid dendritic cell activation - Cellular & Molecular Immunology - 11 month(s) ago
Early and strong interferon type I (IFN-I) responses are usually associated with mild COVID-19 disease, whereas persistent or unregulated proinflammatory cytokine responses are associated with severe disease outcomes. Previous work suggested that monocyte-derived macrophages (MDMs) are resistant and unresponsive to SARS-CoV-2 infection. Here, we demonstrate that upon phagocytosis of…
Source: NatureCategories: Infectious Disease, Latest HeadlinesTweet-
Scientists at @ivi_switzerland describe a novel and potent pathway of plasmacytoid #DendriticCell activation 🔛 that is linked to the #macrophage-mediated clearance of #SARSCoV2 infected cells. #OpenAccess: 📖 https://t.co/e4qTyenFL4 https://t.co/ji8wi2efq2
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Mashup Score: 0FPR2 Shapes an Immune-Excluded Pancreatic Tumor Microenvironment and Drives T-cell Exhaustion in a Sex-Dependent Manner - 11 month(s) ago
FPR2 is a sex-dependent mediator of macrophage function in pancreatic cancer and can be targeted to reprogram macrophages and stimulate antitumor immunity in females.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
In the latest issue— Fei He, @DhifafSarhan et al. find that FPR2 is a sex-dependent mediator of #macrophage function in #pancreaticcancer that can be targeted to reprogram macrophages and stimulate antitumor immunity. https://t.co/4Ipr8CAJZc @karolinskainst https://t.co/6g1aIxmftX
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Mashup Score: 4
Welcome! You are invited to join a webinar: Frontiers in Cardiovascular Science Seminar. After registering, you will receive a confirmation email about joining the webinar.
Source: ZoomCategories: Cardiologists, Latest HeadlinesTweet-
Please join @StanfordCVI seminar on Tue 5/23 at 12-1pm PST by @SDPrabhuMD @WashUCardiology speak on #macrophage, #inflammation, and #heartfailure Zoom link: https://t.co/oD1xyw95rv @StanfordDeptMed @Stanford_ChEMH @SeanM_Wu @ISHR_NAS @vascularbiology @AHAScience @HFSA @ISHLT https://t.co/x0bUCV7EmG
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Mashup Score: 0Exosomal Non-Coding RNAs: Novel Regulators of Macrophage-Linked Intercellular Communication in Lung Cancer and Inflammatory Lung Diseases - 1 year(s) ago
Macrophages are innate immune cells and often classified as M1 macrophages (pro-inflammatory states) and M2 macrophages (anti-inflammatory states). Exosomes are cell-derived nanovesicles that range in diameter from 30 to 150 nm. Non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs), are abundant in exosomes and exosomal ncRNAs…
Source: MDPICategories: Latest Headlines, PulmonologyTweet-
#Exosomal Non-Coding #RNAs: Novel #Regulators of #Macrophage-Linked #Intercellular #Communication in #LungCancer and #Inflammatory #Lung #Diseases https://t.co/tfzZsXTemc https://t.co/1vEOYO6ZyX
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Mashup Score: 3The Kiss of the Macrophage | Center for Cancer Research - 1 year(s) ago
Cancer’s excessive, uncontrolled growth is its most malicious trait. But there is reason to believe that only a tiny and elusive subset of cancer cells truly drive a tumor’s growth: the so-called cancer stem cells. These cells’ unusual resilience and ability to divide in stressful settings may also make them efficient instigators of metastasis, which occurs when cells break off from a primary…
Source: ccr.cancer.govCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
WATCH : To access the bloodstream 🩸 and travel to other parts of the body, cancer cells must pass through a portal made up of three cells. Understanding this process better may help researchers prevent cancer spread. https://t.co/CnMc6zbpjq #macrophage @NCIResearchCtr https://t.co/KiFZmtVFRV
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Mashup Score: 3Arginase 1 Expression by Macrophages Promotes Cryptococcus neoformans Proliferation and Invasion into Brain Microvascular Endothelial Cells - 1 year(s) ago
Key Points. Arginase-1 is induced within alveolar macrophages during C. neoformans infection.Macrophage-derived arginase promotes C. neoformans growth and proli
Categories: Allergy-Immunology, Latest HeadlinesTweet-
#JI_TopRead from Pornpimon Angkasekwinai @thammasat_uni | #Cryptococcusneoformans manipulates #macrophage polarization via upregulation of #Arginase1 to drive fungal #meningoencephalitis | #ReadTheJI #fungalimmunology 👉 https://t.co/JzvFUJTlY7 https://t.co/N63vHypig7
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Gao et al. demonstrated that effective clearance of apoptotic #cardiomyocytes through #efferocytosis is critical for resolving cardiac #inflammation. Learn how mitochondrial iron disorder can lead to proinflammatory #macrophage activation https://t.co/6Mmyo3efqT https://t.co/yS4nVcAWtc