• Mashup Score: 3

    Case studies of patients with anorexia nervosa revealed psychological improvements upon treatment with recombinant human leptin, including an alleviation of the entrapment in this eating disorder. Hypoleptinaemia induced by loss of adipose tissue mass might trigger psychological changes observed in starvation. Accordingly, leptin analogues might prove beneficial for treatment of anorexia nervosa.

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    • In our August issue: a Comment from Anke Hinney and colleagues discusses how #leptin substitution therapy could potentially mitigate symptoms of #anorexia nervosa (£) https://t.co/zW12wJEWC6 @HinneyAnke @MedEssen @UniklinikEssen @unidue @fgf_nrw @MedizinNRW https://t.co/tmMvwo0nwL

  • Mashup Score: 2

    Case studies of patients with anorexia nervosa revealed psychological improvements upon treatment with recombinant human leptin, including an alleviation of the entrapment in this eating disorder. Hypoleptinaemia induced by loss of adipose tissue mass might trigger psychological changes observed in starvation. Accordingly, leptin analogues might prove beneficial for treatment of anorexia nervosa.

    Tweet Tweets with this article
    • Online now: A Comment from @HinneyAnke and colleagues discusses how #leptin substitution therapy could potentially mitigate symptoms of #anorexia nervosa (£) https://t.co/zW12wJEoMy @MedEssen @UniklinikEssen @unidue @fgf_nrw @MedizinNRW https://t.co/ZIBbYgWWB9

  • Mashup Score: 1

    Perhaps the most unexpected development in pediatric endocrinology in the past 50 years has been the recognition of obesity as an endocrine/metabolic disorder rather than a life choice or moral failing. The history of obesity research is disjointed, having followed two separate paths in the 20th century, based on two independent yet overlapping par

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    • RT @EndoKarger: The History of #Obesity Research 🔗 https://t.co/bab3MF3W2b ✍ Nakamura S. et al. 📖 #HormResPaediatr #FreeAccess #Leptin #C…

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    The FDA-approved rheumatoid arthritis drug auranofin accumulates in white adipose tissue, improves insulin sensitivity, and normalizes fatty-liver disease in obesity. Beta-adrenergic receptor regulation of leptin secretion generates metabolic benefits superior to anti-inflammatory effects. Consequently, studies of auranofin reinforce that partial leptin reduction represents a relevant method for…

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    • Researchers have long attempted to find a drug that lowers #leptin. Have they found one? The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice: Cell Metabolism #obesity #weight #weightloss https://t.co/qhouF3GlDK

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    June 30, 2022 — Before a baby is ever born, critical supply chain problems with nutrition and oxygen can result in premature birth or even death and increase the child and mother’s lifelong risk of cardiovascular disease.  Scientists have found that a midgestation increase in the hormone leptin, which most of us associate with appetite suppression, produces problematic blood vessel dysfunction…

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    • @DAICeditor Scientists have found that a #midgestation increase in the #hormone #leptin produces problematic blood vessel dysfunction and restriction of the baby’s growth in #preeclampsia that put mother and baby at risk: https://t.co/ay6WeIEeHA