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Mashup Score: 0Efanesoctocog alfa shows superior bleed protection in patients with severe hemophilia A - 2 year(s) ago
A once-weekly dose of prophylactic efanesoctocog alfa conferred a significant reduction in annualized bleed rate compared with the use of prophylactic factor VIII agents, results of the pivotal phase 3 XTEND-1 study showed. Data from the trial, presented at International Society on Thrombosis and Haemostasis 2022 Congress, revealed that prophylactic efanesoctocog alfa (Sobi, Sanofi) offered
Source: www.healio.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Fitusiran prophylaxis leads to 61% reduction in bleeds among people with hemophilia A or B - 2 year(s) ago
Once-monthly prophylactic fitusiran resulted in significantly fewer bleeding episodes compared with episodic-based on-demand treatment among males with hemophilia A or B with or without inhibitors, according to results of a phase 3 study. Use of fitusiran (Sanofi) also led to significantly improved health-related quality-of-life scores, findings presented at International Society on Thrombosis
Source: www.healio.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
Gili Kenet (Tel Aviv, Israel) presented results from the phase 3 ATLAS-PPX trial (NCT03549871) of the siRNA therapeutic fitusiran in men and boys 12 aged years and older with haemophilia A or B who have previously been treated with factor or bypassing agent (BPA). Patients continued on their previous treatment for 6 months, then switched to 80 mg subcutaneous fitusiran prophylaxis once per month…
Source: The Lancet HaematologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Expression of coagulation inhibitors in the immune microenvironment in precursor stages of myeloma - 2 year(s) ago
In this video, Xue-Yan Cui, MD, PhD, Oslo University Hospital, Oslo, Norway, discusses her poster presentation from ISTH 2022, which…
Source: VJHemOncCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0COVID-19 vaccination in patients with ITP - 2 year(s) ago
Hanny Al-Samkari, MD, Massachusetts General Hospital, Harvard Medical School, Boston, MA, comments on the safety of COVID-19 vaccination in patients…
Source: VJHemOncCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0The safety and efficacy of fitusiran prophylaxis in patients with hemophilia A and B - 2 year(s) ago
Alok Srivastava, MD, FRACP, FRCPA, FRCP, Christian Medical College, Vellore, India, discusses his presentation at ISTH 2022, which focused on…
Source: VJHemOncCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Managing pregnant women with vWD - 2 year(s) ago
Susan Halimeh, MD, Gerinnungszentrum Rhein-Ruhr, Duisburg, Germany, outlines the challenges associated with managing pregnant women with von Willebrand disease (vWD)….
Source: VJHemOncCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Offering personalized therapy to young and elderly patients with non-severe hemophilia - 2 year(s) ago
Oliver Königsbrügge, MD, PhD, Medical University of Vienna, Vienna, Austria, emphasizes the importance of selecting appropriate treatments for both young…
Source: VJHemOncCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 2
Priyanka Raheja, MBBS, MD, Royal London Hospital, London, UK, talks on immune response monitoring in patients with hemophilia treated with…
Source: VJHemOncCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Therapeutic potential of IdeS in hemophilia A with inhibitors - 2 year(s) ago
Melissa Bou Jaoudeh, PhD, Sorbonne University, Paris, France, comments on the therapeutic potential of IdeS for the treatment of patients…
Source: VJHemOncCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
NEWS from #ISTH2022 A once-weekly dose of prophylactic efanesoctocog alfa conferred a significant reduction in annualized bleed rate compared with the use of prophylactic factor VIII agents, phase 3 XTEND-1 study shows. https://t.co/qBWSaeAXTH @UCSDHealth