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Mashup Score: 14Dysregulation of the Environmental Sensor Aryl Hydrocarbon Receptor Affects Differentiation of Human Colon Organoids - 1 month(s) ago
Gut disorders such, as inflammatory bowel disease (IBD), have increased dramatically in the past 50 years, driven by incompletely defined environmental factors including diet, with reduced intake of substances such as indole compounds, which function as aryl hydrocarbon receptor (AHR) ligands. The AHR resides in the cytoplasm complexed with chaperones, and upon ligand binding translocates to the nucleus where it dimerizes with its partner aryl hydrocarbon nuclear translocator, and initiates the transcription of a wide range of target genes.
Source: www.cmghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 12Defining Small Intestinal Bacterial Overgrowth by Culture and High Throughput Sequencing - 2 month(s) ago
Despite accelerated research in small intestinal bacterial overgrowth (SIBO), questions remain regarding optimal diagnostic approaches and definitions. Here, we aim to define SIBO using small bowel culture and sequencing, identifying specific contributory microbes, in the context of gastrointestinal symptoms.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 1Caffeine Limits Expansion of Apc-Deficient Clones in the Intestine by NOTUM Inhibition - 6 month(s) ago
Colorectal cancer (CRC) development is characterized by stepwise accumulation of mutations, of which the majority display early mutations in tumor suppressor gene APC.1 Previous work revealed that Apc loss confers a competitive advantage to mutant intestinal stem cells (ISCs), which consequently replace all normal ISCs and drive crypt fixation in vivo.2 Recent studies demonstrate that this advantage can be attributed to the secretion of Wnt antagonists (eg, NOTUM/WIF1/DKK2) that drive normal ISC differentiation.
Source: www.cmghjournal.orgCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Intestinal anastomoses in children. Draft decision of the Russian Symposium of Children surgeons, April 2023 - 10 month(s) ago
Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care – Articles in press
Categories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 0Wolters Kluwer Health - 11 month(s) ago
JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…
Source: lww.comCategories: Latest Headlines, PediatricsTweet
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Mashup Score: 1sCD14 and intestinal fatty acid binding protein are elevated in the serum of patients with idiopathic anaphylaxis. - 12 month(s) ago
Intestinal epithelial integrity compromise has been identified in gastrointestinal (GI), atopic, and autoimmune diseases.
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 1
Study shows bowel wall thickness was the best parameter of therapeutic response and remission
Source: www.medpagetoday.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 8
Share on PinterestA new study points to the gut virome as the culprit in intestinal bowel disease. NIH/NAID/IMAGE.FR/BSIP/Universal Images Group via Getty ImagesThe human microbiome contains a community of microorganisms that include viruses. This is called the human virome, a community of both beneficial and pathogenic viruses.The virome begins at birth and may be an equally important factor in…
Source: www.medicalnewstoday.comCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 0Researchers present cellular atlas of the human gut - 2 year(s) ago
Using human gastrointestinal tracts from three organ donors, researchers shed renewed insight into the function of different cell types across intestinal regions.
Source: www.mdedge.comCategories: Latest Headlines, OBGYNTweet
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Mashup Score: 0Researchers present cellular atlas of the human gut - 2 year(s) ago
Using human gastrointestinal tracts from three organ donors, researchers shed renewed insight into the function of different cell types across intestinal regions.
Source: www.mdedge.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
Research Letter's data indicates that evolutionary conserved functions of AHR in #intestinal epithelial cells shape the regeneration and differentiation of intestinal stem cells not only in mice, but also in humans. Learn more at https://t.co/K0IcD4X7Yw https://t.co/HTaRNjCdwS