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Mashup Score: 1FMT future ‘still being written,’ ideally with more options for recurrent C. difficile - 5 month(s) ago
From the early days of homemade “poop shakes” blended in a backroom 15 years ago to the current world of FDA-approved live biotherapeutic products, it feels like we are at an inflection point with fecal microbiota transplantation.With credit to Robert Hunter, collaborator and lyricist for the Grateful Dead: “What a long, strange trip it’s been.”
Source: www.healio.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 4Rome consensus on gut microbiota and faecal microbiota transplantation in IBD | Gut Podcast - 6 month(s) ago
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, UK, interviews Professor Loris Lopetuso, Department of Medicine and Ageing Sciences, University of Chieti-Pescara, Italy, on the paper “The first international Rome consensus conference on gut microbiota and faecal microbiota transplantation in inflammatory bowel disease”, published in paper copy in Gut in September 2023, and available online: https://gut.bmj.com/content/72/9/1642 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
Source: gutbmj.podbean.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 2The first international Rome consensus conference on gut microbiota and faecal microbiota transplantation in inflammatory bowel disease - 7 month(s) ago
Background Several randomised clinical trials (RCTs) performing faecal microbiota transplantation (FMT) for the management of inflammatory bowel disease (IBD), particularly for ulcerative colitis, have recently been published, but with major variations in study design. These include differences in administered dose, route and frequency of delivery, type of placebo and evaluated endpoints. Although the overall outcomes appear to be promising, they are highly dependent on both donor and recipient factors. Objective To develop concensus-based statements and recommendations for the evaluation, management and potential treatment of IBD using FMT in order to move towards standardised practices. Design An international panel of experts convened several times to generate evidence-based guidelines by performing a deep evaluation of currently available and/or published data. Twenty-five experts in IBD, immunology and microbiology collaborated in different working groups to provide statements on
Source: gut.bmj.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Meta-Analysis Finds High Rates of Clinical, Endoscopic Remission Among Patients With UC Treated With FMT - 7 month(s) ago
Investigators observed higher rates of clinical and endoscopic remission among patients with UC treated with FMT compared to those on control treatments, further noting comparable rates of adverse reactions between the groups.
Source: www.hcplive.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 2Rome consensus on gut microbiota and faecal microbiota transplantation in IBD | Gut Podcast - 7 month(s) ago
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, UK, interviews Professor Loris Lopetuso, Department of Medicine and Ageing Sciences, University of Chieti-Pescara, Italy, on the paper “The first international Rome consensus conference on gut microbiota and faecal microbiota transplantation in inflammatory bowel disease”, published in paper copy in Gut in September 2023, and available online: https://gut.bmj.com/content/72/9/1642 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
Source: gutbmj.podbean.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 6The first international Rome consensus conference on gut microbiota and faecal microbiota transplantation in inflammatory bowel disease - 7 month(s) ago
Background Several randomised clinical trials (RCTs) performing faecal microbiota transplantation (FMT) for the management of inflammatory bowel disease (IBD), particularly for ulcerative colitis, have recently been published, but with major variations in study design. These include differences in administered dose, route and frequency of delivery, type of placebo and evaluated endpoints. Although the overall outcomes appear to be promising, they are highly dependent on both donor and recipient factors. Objective To develop concensus-based statements and recommendations for the evaluation, management and potential treatment of IBD using FMT in order to move towards standardised practices. Design An international panel of experts convened several times to generate evidence-based guidelines by performing a deep evaluation of currently available and/or published data. Twenty-five experts in IBD, immunology and microbiology collaborated in different working groups to provide statements on
Source: gut.bmj.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Rome consensus on gut microbiota and faecal microbiota transplantation in IBD | Gut Podcast - 7 month(s) ago
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, UK, interviews Professor Loris Lopetuso, Department of Medicine and Ageing Sciences, University of Chieti-Pescara, Italy, on the paper “The first international Rome consensus conference on gut microbiota and faecal microbiota transplantation in inflammatory bowel disease”, published in paper copy in Gut in September 2023, and available online: https://gut.bmj.com/content/72/9/1642 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
Source: gutbmj.podbean.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0
Fecal microbiota transplantation improved gut barrier function, mucosal immunity and ammonia metabolism in patients with cirrhosis, which could reduce hepatic encephalopathy and other infections, according to data from the PROFIT trial. “Patients with cirrhosis have enteric dysbiosis,” Lindsey A. Edwards, BSC, MSc, PhD, research director of fecal microbiota transplant program at
Source: www.healio.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 1Evaluating the Benefits and Risks of Fecal Microbiota Transplantation for Recurrent C diff - 10 month(s) ago
FMT is a promising intervention for immunocompetent patients with recurrent C difficile infection. However, the safety of FMT remains inconclusive due to limited data on serious adverse events and mortality.
Source: ContagionLiveCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 1NEJM Journal Watch: Summaries of and commentary on original medical and scientific articles from key medical journals - 11 month(s) ago
NEJM Journal Watch reviews over 250 scientific and medical journals to present important clinical research findings and insightful commentary
Source: www.jwatch.orgCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
“The future of #FMT is still being written,” @DrStollman said in response. “I greet that future with a great deal of optimistic excitement, but still with a bit of trepidation.” Read the full expert editorial here 👇🏻 https://t.co/gkdkkZPXSO