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Mashup Score: 30Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer - 2 year(s) ago
RSK4 promotes invasiveness and drug resistance in lung and bladder cancer and inhibition of this kinase shows therapeutic potential.
Source: Science Translational MedicineCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 24Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer - 2 year(s) ago
RSK4 promotes invasiveness and drug resistance in lung and bladder cancer and inhibition of this kinase shows therapeutic potential.
Source: Science Translational MedicineCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 62Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer - 3 year(s) ago
Lung and bladder cancers are difficult to treat because of the development of drug-refractory metastases. Chrysostomou et al. show that the p90 ribosomal protein S6 kinase 4 (RSK4) is involved in the development of chemotherapy resistance and metastatic invasion in both in vitro and in vivo models. Identification of a binding site for floxacin antibiotics on RSK4 led to the finding that…
Source: Science Translational MedicineCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 79Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer - 3 year(s) ago
Lung and bladder cancers are difficult to treat because of the development of drug-refractory metastases. Chrysostomou et al. show that the p90 ribosomal protein S6 kinase 4 (RSK4) is involved in the development of chemotherapy resistance and metastatic invasion in both in vitro and in vivo models. Identification of a binding site for floxacin antibiotics on RSK4 led to the finding that…
Source: Science Translational MedicineCategories: Future of Medicine, Latest HeadlinesTweet
Studies of mice and data from patients with #BladderCancer and #LungCancer show that #floxacin antibiotics can suppress both chemotherapy resistance and tumor metastasis, two major causes of cancer relapse and mortality. https://t.co/zXpp7nLMRt @ScienceTM https://t.co/EbVr6ZoYyT