• Mashup Score: 2

    Xylazine is an animal sedative, approved by the U.S. Food and Drug Administration, that is commonly used in veterinary medicine and is not approved for human use. Since 2016, xylazine has consistently appeared in the illicitly manufactured fentanyl supply and has significantly increased in prevalence, likely due to its low cost, easy availability, and presumed synergistic psychoactive effect. Clinical experience along with the available pertinent research were used to review xylazine adulteration of the drug supply and provide guidance on the care of patients exposed to xylazine. This review discusses xylazine pharmacology, animal and human clinical effects, and what is known to date about care of patients experiencing acute overdose, xylazine–fentanyl withdrawal, and xylazine-associated wounds.

    Tweet Tweets with this article
    • A new narrative review offers guidance on the care of patients exposed to #xylazine, or #tranq, an animal sedative that has made its way into the illicitly manufactured #fentanyl supply: https://t.co/kqGRZXjRut https://t.co/5x706Sgq2x

  • Mashup Score: 0

    With the growing prevalence of the animal tranquilizer xylazine, or ‘tranq,’ more testing and research will be key, according to a new study.

    Tweet Tweets with this article
    • The widening threat of the animal tranquilizer xylazine, otherwise known as #tranq, which has been found in illegally manufactured #fentanyl, necessitates wider testing, a better understanding of its effects, and more research on treatment options. https://t.co/9dbtXIOhUD

  • Mashup Score: 0

    Xylazine is an animal sedative, approved by the U.S. Food and Drug Administration, that is commonly used in veterinary medicine and is not approved for human use. Since 2016, xylazine has consistently appeared in the illicitly manufactured fentanyl supply and has significantly increased in prevalence, likely due to its low cost, easy availability, and presumed synergistic psychoactive effect. Clinical experience along with the available pertinent research were used to review xylazine adulteration of the drug supply and provide guidance on the care of patients exposed to xylazine. This review discusses xylazine pharmacology, animal and human clinical effects, and what is known to date about care of patients experiencing acute overdose, xylazine–fentanyl withdrawal, and xylazine-associated wounds.

    Tweet Tweets with this article
    • A new narrative review offers guidance on the care of patients exposed to #xylazine, or #tranq, an animal sedative that has made its way into the illicitly manufactured #fentanyl: https://t.co/kqGRZXkpk1 https://t.co/yROuNFwhd3