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    Stegemann et al. have unraveled a long-lasting role for fear engrams in future pain perception. Prefrontal pain and fear representations become entangled following a fearful event. As subsequent painful experiences also reactivate the fear network, silencing the fear engram alone can alleviate both tonic pain and hypersensitivity in chronic pain.

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    • #Fear memory #engram is the mind-killer Nice N&V by @GisellaVetere 👊🏼https://t.co/GsfxRhVgYW #PrefrontalCortex #Hyperalgesia #Allodynia #ChronicPain Prefrontal engrams of long-term #fearmemory perpetuate #pain perception @Nature https://t.co/XDAP1fOiBV SNI- Spared Nerve… https://t.co/njhvPGx6hn https://t.co/xUCdoXCEgU

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    Some experts think that feelings of fear might actually be good for you.

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    • If you love horror movies and haunted houses, you might wonder whether being scared could be good for your health. 👻 This Happy Halloween, explore the benefits of being spooked — and when fear is definitely *not* helpful. #fear #healthy https://t.co/7pmVTwQKgD

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    Exposure therapy for fears and phobias may only have a 50% success rate because fear memories outlast competing safety memories learned from therapy. Researchers investigate the genesis of fear memories and have developed a new mathematical model to help strengthen exposure therapies.

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    • Where Do Fears Come From? Researchers investigate the genesis of fear memories and have developed a new mathematical model to help strengthen exposure therapies. #fear #neuroscience #science https://t.co/mtqlcuI3E5

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    Researchers at Linköping University, Sweden, have discovered a biological mechanism that increases the strength with which fear memories are stored in the brain. The study, carried out in rats, is published in Molecular Psychiatry. It provides new knowledge on the mechanisms behind anxiety-related disorders, and identifies shared mechanisms behind anxiety and alcohol dependence.

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    • How #fear memories get stuck in some brains https://t.co/GBswSAh8m4

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    Norepinephrine facilitates fear processing by stimulating a population of inhibitory neurons in the amygdala, generating repetitive bursting patterns of electrical activity. This activity changes the frequency of oscillations in the amygdala from resting state to aroused state, promoting the formation of fear memories.

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    • Norepinephrine facilitates fear processing by stimulating a population of inhibitory neurons in the amygdala, generating repetitive bursting patterns of electrical activity. #fear #ptsd #neuroscience #science https://t.co/RR5CqtS3Cm