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Mashup Score: 1EULAR: Physical activity, regular assessment recommended for fatigue in inflammatory RMD - 2 month(s) ago
Fatigue in patients with inflammatory rheumatic and musculoskeletal diseases should be addressed with tailored physical activity, psychoeducational interventions or possibly immunomodulatory treatment, according to EULAR recommendations. “Fatigue is prevalent in people with [inflammatory rheumatic and musculoskeletal diseases (I-RMDs)] and is one of the most challenging symptoms to cope
Source: www.healio.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 0Cancer‐related fatigue: Towards a more targeted approach based on classification by biomarkers and psychological factors - 3 month(s) ago
Fatigue associated with cancer frequently persists years after treatment, often with consequences for quality of life. Moreover, fatigue is commonly treated in an undifferentiated manner, owing to a …
Source: onlinelibrary.wiley.comCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 422023 EULAR recommendations for the management of fatigue in people with inflammatory rheumatic and musculoskeletal diseases - 4 month(s) ago
Objectives Fatigue is prevalent in people with inflammatory rheumatic and musculoskeletal diseases (I-RMDs) and recognised as one of the most challenging symptoms to manage. The existence of multiple factors associated with driving and maintaining fatigue, and the evidence about what improves fatigue has led to a multifaceted approach to its management. However, there are no recommendations for fatigue management in people with I-RMDs. This lack of guidance is challenging for those living with fatigue and health professionals delivering clinical care. Therefore, our aim was to develop EULAR recommendations for the management of fatigue in people with I-RMDs. Methods A multidisciplinary taskforce comprising 26 members from 14 European countries was convened, and two systematic reviews were conducted. The taskforce developed the recommendations based on the systematic review of evidence supplemented with taskforce members’ experience of fatigue in I-RMDs. Results Four overarching princip
Source: ard.bmj.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 2Dichloroacetate as a novel pharmaceutical treatment for cancer-related fatigue in melanoma | American Journal of Physiology-Endocrinology and Metabolism - 6 month(s) ago
Cancer-related fatigue (CRF) is one of the most common complications in patients with multiple cancer types and severely affects patients’ quality of life. However, there have only been single symptom-relieving adjuvant therapies but no effective pharmaceutical treatment for the CRF syndrome. Dichloroacetate (DCA), a small molecule inhibitor of pyruvate dehydrogenase kinase, has been tested as a potential therapy to slow tumor growth, based largely on its effects in vitro to halt cell division. We found that although DCA did not affect rates of tumor growth or the efficacy of standard cancer treatment (immunotherapy and chemotherapy) in two murine cancer models, DCA preserved physical function in mice with late-stage tumors by reducing circulating lactate concentrations. In vivo liquid chromatography-mass spectrometry/mass spectrometry studies suggest that DCA treatment may preserve membrane potential, postpone proteolysis, and relieve oxidative stress in muscles of tumor-bearing mice.
Source: journals.physiology.orgCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Intervention with Supplemental Creatine Found Effective, Safe for Symptom Reduction After COVID-19 Infection - 6 month(s) ago
At a 6-month follow-up, supplemental creatine intervention significantly improved scores for fatigue symptoms and tissue bioenergetics related to COVID-19 infection.
Source: www.pharmacytimes.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 0Are You Too Fatigued to Work Out? Here’s How to Tell - 6 month(s) ago
Explore the importance of exercise and managing fatigue. Learn when to push through and when to consult your doctor.
Source: creakyjoints.orgCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 1Interventions for fatigue in people with kidney failure requiring dialysis - Natale, P - 2023 | Cochrane Library - 7 month(s) ago
Collapse all Expand all Background Fatigue is a common and debilitating symptom in people receiving dialysis that is associated with an increased risk of death, cardiovascular disease and depression. Fatigue can also impair quality of life (QoL) and the ability to participate in daily activities. Fatigue has been established by patients, caregivers and health professionals as a core…
Source: www.cochranelibrary.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0A protein that disrupts cells’ energy centers may be a culprit in chronic fatigue syndrome - 8 month(s) ago
New study offers clues as to how exhaustion could arise in people with ME/CFS—and potentially related conditions such as Long Covid
Source: www.science.orgCategories: Healthcare Professionals, Latest HeadlinesTweet-
A protein that disrupts cells’ energy centers may be a culprit in chronic #fatigue syndrome | Science | AAAS https://t.co/J3RFogyqjh #CFS #MECFS #LongCovid #mitochondria #ERstress #ATP #WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in… https://t.co/e1AzMFvWKM https://t.co/5Nm2URVohL
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Mashup Score: 3Fatigue in Adults: Evaluation and Management - 8 month(s) ago
Fatigue is among the top 10 reasons patients visit primary care offices, and it significantly affects patients’ well-being and occupational safety. A comprehensive history and cardiopulmonary, neurologic, and skin examinations help guide the workup and diagnosis. Fatigue can be classified as physiologic, secondary, or chronic. Physiologic fatigue can be addressed by proper sleep hygiene, a healthy diet, and balancing energy expenditure. Secondary fatigue is improved by treating the underlying condition. Cognitive behavior therapy, exercise therapy, and acupuncture may help with some of the fatigue associated with chronic conditions. Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic, severe, and potentially debilitating disorder with demonstrated inflammatory, neurologic, immunologic, and metabolic abnormalities. ME/CFS has a poor prognosis, with no proven treatment or cure. It may become more common after the COVID-19 pandemic because many patients with long COVI
Source: www.aafp.orgCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 2
Introducing Spondycast, SAA’s new podcast series, that provides the newest and most exciting source of information and inspiration for people with spondyloarthritis. Every week, we bring you in-depth conversations with the leading experts in the field, who will share their knowledge and experience on topics related to the diagnosis, treatment, and management of this complex disease. Whether you…
Categories: Latest Headlines, RheumatologyTweet
New from @eular_org: Recommendations for #fatigue in inflammatory rheumatic and musculoskeletal disease include... 🏃physical activity and 🧠psychoeducational interventions. Read more 👇 https://t.co/UdpivoHi1I