• Mashup Score: 11

    Here, we report a lack of diversity in epigenome-wide association studies (EWAS) and DNA methylation (DNAm) data, discuss current challenges, and propose solutions for EWAS and DNAm research in diverse populations. The strategies we propose include fostering community involvement, new data generation, and cost-effective approaches such as locus-specific analysis and ancestry variable region…

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    • RT @charles_breeze: So glad our work on diversity in EWAS is finally out! 🎉 https://t.co/Nouye1nkEW #genomics #epigenomics #EWAS #diversi…

  • Mashup Score: 1

    We identified DNA methylation sites as epigenetic susceptibility loci for respiratory failure in COVID-19 patients. These candidate biomarkers, combined with other clinical, cellular and genetic factors, could be useful in the clinical stratification and management of patients infected with the SARS-CoV-2.

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    • Grateful to colleagues and fellow scientists for the interest and kind attention given to our #Epigenetics #EWAS article of #COVID-19 #coronavirus, making it among the currently most read manuscripts of @EbioMedicine Published by @TheLancet https://t.co/9oc6fhIKG7 https://t.co/qndX6ijlQF

  • Mashup Score: 6

    We identified DNA methylation sites as epigenetic susceptibility loci for respiratory failure in COVID-19 patients. These candidate biomarkers, combined with other clinical, cellular and genetic factors, could be useful in the clinical stratification and management of patients infected with the SARS-CoV-2.

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    • We found that #Epigenetics #Epigenomics #DNA #Methylation predicts COVID-19 #covid #coronavirus #clinical severity, our #openaccess #EWAS article in @EbioMedicine Published by @TheLancet https://t.co/9oc6fhIKG7 https://t.co/WD5WZ3rSUz

  • Mashup Score: 1

    Objective To assess the association between DNA methylation and acute myocardial infarction, the predictive added value of the identified methylation marks, and the causality of those associations. Approach and Results We conducted a case-control, two-stage, epigenome-wide association study on acute myocardial infarction (ndiscovery=391, nvalidation=204). DNA methylation was assessed using the…

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    • Glad to have participated in discovery of #DNAmethylation #epigenetic biomarkers of #cardiovascular disease using #EWAS on acute #myocardial infarction led by @albafsanles and @RobertoElosua @imimat @CIBER_CV @uvic_ucc, article at @biorxivpreprint https://t.co/u6ZOy95xDv https://t.co/lgztJDFkeE