• Mashup Score: 1

    Optimal risk assessment for primary prevention remains highly challenging. Recent registries have highlighted major discrepancies between guidelines and daily practice. Although guidelines have improved over time and provide updated risk scores, they still fail to identify a significant proportion of at-risk individuals, who then miss out on effective prevention measures until their initial ischemic events. Cardiovascular imaging is progressively assuming an increasingly pivotal role, playing a crucial part in enhancing the meticulous categorization of individuals according to their risk profiles, thus enabling the customization of precise therapeutic strategies for patients with increased cardiovascular risks. For the most part, the current approach to patients with atherosclerotic cardiovascular disease (ASCVD) is homogeneous. However, data from registries (e.g., REACH, CORONOR) and randomized clinical trials (e.g., COMPASS, FOURIER, and ODYSSEY outcomes) highlight heterogeneity in t

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    As noted in JAMA more than 30 years ago,1 randomized clinical trials are like diagnostic tests in several ways. Clinical trials are designed to detect hypothesized treatment effects in the same way diagnostic tests are designed to detect an abnormality or target illness. A trial’s statistical power,…

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    • Revisiting the Analogy Between Clinical Trials and Diagnostic Tests by Interpreting a Negative Trial as a Negative Test for Efficacy. #RCT #EBM https://t.co/kfiDqZrrC6

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    The single maintenance and reliever therapy (SMART) treatment approach to patients with asthma, outlined in the article on chronic asthma treatment in the April issue of American Family Physician, has consistent supporting evidence from multiple randomized controlled trials. A

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    • Have pharmaceutical conflicts of interest unduly influenced asthma guidelines?: The single maintenance and reliever therapy (SMART) treatment approach to patients with asthma has consistent supporting evidence from multiple RCTs. ... https://t.co/DxoE06Obio #EBM h/t @SteveBrownMD

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    Geographic Groups - 12 month(s) ago

    Cochrane Africa NetworkCochrane South AfricaSouth African Medical Research CouncilPO Box 19070TygerbergCape Town7505South Africa Cochrane ArgentinaInstituto de Efectividad Clínica y Sanitaria (IECS-CONICET)Ravigniani 20241099 Buenos AiresCABAArgentina Phone: 1147778767 Fax: 1147778767 Cochrane Argentina (AOA)Cochrane Argentina (Centro Rosarino de Estudios Perinatales)Cochrane Argentina…

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    • 🎉Leonie and Julian won a Cochrane Austria grant and were able to take part in this year's #EBM Congress. 🌐 Connect with your local Cochrane group! Find one in your country here: https://t.co/QEQsnpN3wm https://t.co/xODHFu8oXH

  • Mashup Score: 1
    Departments - 1 year(s) ago

    AFP Department Collections

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