• Mashup Score: 2

    Objective Aberrant lipid metabolism is a hallmark of colorectal cancer (CRC). Squalene epoxidase (SQLE), a rate-limiting enzyme in cholesterol biosynthesis, is upregulated in CRC. Here, we aim to determine oncogenic function of SQLE and its interplay with gut microbiota in promoting colorectal tumourigenesis. Design Paired adjacent normal tissues and CRC from two cohorts were analysed (n=202)….

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    • #GUTImage from the paper "Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis" via https://t.co/MZuRPwlJUq #Dysbiosis https://t.co/hNFfXwLn14

  • Mashup Score: 0

    Objective Aberrant lipid metabolism is a hallmark of colorectal cancer (CRC). Squalene epoxidase (SQLE), a rate-limiting enzyme in cholesterol biosynthesis, is upregulated in CRC. Here, we aim to determine oncogenic function of SQLE and its interplay with gut microbiota in promoting colorectal tumourigenesis. Design Paired adjacent normal tissues and CRC from two cohorts were analysed (n=202)….

    Tweet Tweets with this article
    • #GUTImage from the paper "Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis" via https://t.co/MZuRPw4GSq #Dysbiosis https://t.co/txNabJOa29

  • Mashup Score: 0

    Objective Aberrant lipid metabolism is a hallmark of colorectal cancer (CRC). Squalene epoxidase (SQLE), a rate-limiting enzyme in cholesterol biosynthesis, is upregulated in CRC. Here, we aim to determine oncogenic function of SQLE and its interplay with gut microbiota in promoting colorectal tumourigenesis. Design Paired adjacent normal tissues and CRC from two cohorts were analysed (n=202)….

    Tweet Tweets with this article
    • #GUTImage from the paper "Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis" via https://t.co/MZuRPw492S #Dysbiosis https://t.co/f9qvJ3zMFb

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    The impact of T cell-mediated rejection (TCMR) after liver transplantation (LT) on the alterations in the gut microbiota (GM) and associated intestinal environment represented by fecal organic acids (OAs) require further elucidation. A rat allogeneic LT model was prepared without immunosuppressants or antibiotics, and a syngeneic model was used as a control. Qualitative and quantitative analyses…

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    • New insights in #dysbiosis of #gut #microbiota and depletion of fecal organic acids on deterioration of #graft #function caused by #TCMR in #LiverTransplant, without intervention, including fasting, immunosuppressant, and antibiotic use https://t.co/HXikVilbLg https://t.co/UkC7n1446D

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    Evidence is strong that sexual partners transmit microbiota (bacteria, viruses, fungi, protozoa, and archaea) to each other. While microbial flora are abundant in the gastrointestinal tract, they are also present in the vagina, penis, urethra, mouth, and skin.1

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    • Investigators have discovered that sexual contact of all types means that participants will acquire each other’s microbiota. Learn how that may increase the risk of #dysbiosis and psychiatric disorders. https://t.co/vmk6o6iKgw #CurrentPsychiatry https://t.co/0qhLhXAU68