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Mashup Score: 0
Thiostrepton (TST) is a natural antibiotic with pleiotropic properties. This study aimed to elucidate the therapeutic effect of TST on experimental colitis and identify its targets. The effect of TST […]
Source: www.iasp-pain.orgCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 1
Cell Symposium: Cell Symposia: Infection Biology in the Age of the Microbiome
Source: www.cell-symposia.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 0
Cell Symposium: Cell Symposia: Infection Biology in the Age of the Microbiome
Source: www.cell-symposia.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 2Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis - 1 year(s) ago
Objective Aberrant lipid metabolism is a hallmark of colorectal cancer (CRC). Squalene epoxidase (SQLE), a rate-limiting enzyme in cholesterol biosynthesis, is upregulated in CRC. Here, we aim to determine oncogenic function of SQLE and its interplay with gut microbiota in promoting colorectal tumourigenesis. Design Paired adjacent normal tissues and CRC from two cohorts were analysed (n=202)….
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis - 1 year(s) ago
Objective Aberrant lipid metabolism is a hallmark of colorectal cancer (CRC). Squalene epoxidase (SQLE), a rate-limiting enzyme in cholesterol biosynthesis, is upregulated in CRC. Here, we aim to determine oncogenic function of SQLE and its interplay with gut microbiota in promoting colorectal tumourigenesis. Design Paired adjacent normal tissues and CRC from two cohorts were analysed (n=202)….
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis - 1 year(s) ago
Objective Aberrant lipid metabolism is a hallmark of colorectal cancer (CRC). Squalene epoxidase (SQLE), a rate-limiting enzyme in cholesterol biosynthesis, is upregulated in CRC. Here, we aim to determine oncogenic function of SQLE and its interplay with gut microbiota in promoting colorectal tumourigenesis. Design Paired adjacent normal tissues and CRC from two cohorts were analysed (n=202)….
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Dysbiosis and Depletion of Fecal Organic Acids Correlate With the Severity of Rejection After Rat Liver Transplantation - 2 year(s) ago
The impact of T cell-mediated rejection (TCMR) after liver transplantation (LT) on the alterations in the gut microbiota (GM) and associated intestinal environment represented by fecal organic acids (OAs) require further elucidation. A rat allogeneic LT model was prepared without immunosuppressants or antibiotics, and a syngeneic model was used as a control. Qualitative and quantitative analyses…
Source: FrontiersCategories: Latest Headlines, TransplantationTweet
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Mashup Score: 4
Background: Preeclampsia is one of the leading causes of maternal and perinatal morbidity and is characterized by hypertension, inflammation, and placental dysfunction. Gut microbiota plays key roles
Source: Circulation ResearchCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Gut Microbiota Dybiosis May Be Linked to Rheumatic Disease - 2 year(s) ago
Developing research into the specific alterations of dysbiosis and diseases like arthritis suggest possibly novel pathways to therapy development.
Source: HCPLive®Categories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0
Evidence is strong that sexual partners transmit microbiota (bacteria, viruses, fungi, protozoa, and archaea) to each other. While microbial flora are abundant in the gastrointestinal tract, they are also present in the vagina, penis, urethra, mouth, and skin.1
Source: www.mdedge.comCategories: Latest Headlines, PediatricsTweet
New in PRF’s #PapersoftheWeek read an article on how #thiostrepton alleviates experimental #colitis by promoting #RORγt ubiquitination and modulating #dysbiosis. https://t.co/DQaKQQkpB0