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    Impaired wound healing in the diabetic foot is a major problem often leading to amputation. Mast cells have been shown to regulate wound healing in diabetes. We developed an indole-carboxamide type mast cell stabilizer, MCS-01, which proved to be an effective mast cell degranulation inhibitor in vitro and can be delivered topically for prolonged periods through controlled release by specifically…

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    • Topical Application of a Mast Cell Stabilizer Improves Impaired Diabetic Wound Healing https://t.co/ZAXOUaAkRS #woundhealing #DFU #topical https://t.co/9bH9SEuQq6