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    Author links open overlay panel Christoph M. Hammers 1 2 Over the past decade, much progress has been made in decoding autoimmune mechanisms at all stages of this paradigmatic model disease, with important input stemming from omics-based high-throughput technologies: antibody and/or B-cell receptor repertoires of patients with pemphigus were studied in great detail and partly over time by antibody phage display (Payne et al., 2005), Epstein−Barr virus−transformed hybridoma cells (Di Zenzo et al., 2012),

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    Author links open overlay panel Nehal N. Mehta 1 2 NM serves as a board member of the American Society of Preventive Cardiology (unpaid), a member of the National Psoriasis Foundation Scientific Advisory Committee (unpaid), has received grants, research and/or consulting fees from Abbvie, Novartis, Amgen, Lilly, Bristol Myers Squibb, Sun, Janssen, Abcentra, none of which relate to the current publication. The author would like to express gratitude to Alvaro Cantero Gonzalez for his editorial assistance

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    The concept of a second skin or electronic skin (e-skin) is currently a hot topic, reflecting technological advances in electronics, polymers, and nanotechnology, but this subject has not yet reached the mainstream of skin biologists, dermatologists, and the wider medical community. These recently developed devices are proving to be useful in monitoring systemic health across the skin surface with far greater precision than typical electrode-based devices. Moreover, e-skins are being designed to extract and monitor samples of body fluids continuously as well as to improve transdermal drug delivery.

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