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Mashup Score: 4Tafolecimab in Chinese Patients With Hypercholesterolemia (CREDIT-4): A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial - 7 month(s) ago
Abstract Background Tafolecimab is a novel fully human proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibody, developed for the treatment of hypercholesterolemia. Objectives The…
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Mashup Score: 0LDL-C Reduction With Lipid-Lowering Therapy for Older Individuals - American College of Cardiology - 7 month(s) ago
Melvyn Rubenfire, MD, FACC
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Mashup Score: 3High-Throughput Microscopy Characterization of Rare LDLR Variants: - 7 month(s) ago
Highlights • Around 40% of LDLR variants are classified as VUS, posing as the biggest hurdle to reach a definitive FH diagnosis. • We optimized and validated a time- and cost-effective high-through…
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Mashup Score: 2Treatment of ATTR Amyloidosis - American College of Cardiology - 12 month(s) ago
A 76-year-old man with a medical history of hypertension, hyperlipidemia, type 2 diabetes mellitus, carpal tunnel syndrome, and benign prostatic hypertrophy was recently diagnosed with wildtype transthyretin (ATTR) cardiac amyloidosis with preserved left ventricular ejection fraction of 51% on echocardiography. He does not have a known history of atrial fibrillation or coronary artery disease. He…
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Mashup Score: 31Heart Failure Fact or Fiction: BP, How Low Is Too Low? - American College of Cardiology - 12 month(s) ago
A 71-year-old man with heart failure with reduced ejection fraction (HFrEF; 30%) due to ischemic cardiomyopathy, hypertension, and hyperlipidemia is admitted for acute decompensated heart failure (HF). He received 3 days of intravenous furosemide and optimization of guideline-directed medical therapy (GDMT). He is now euvolemic. He reports dizziness with ambulation this morning during bedside…
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Mashup Score: 2Heart Failure Fact or Fiction: Creatinine's Cautionary Tale - American College of Cardiology - 12 month(s) ago
A 68-year-old woman with heart failure with reduced ejection fraction (HFrEF; left ventricular ejection fraction 35%), hypertension, hyperlipidemia, and stable chronic kidney disease (CKD) is seen in the clinic 2 weeks after admission for acute decompensated heart failure (HF), for which she required several days of intravenous diuresis. She was discharged on her previous medications: metoprolol…
Source: American College of CardiologyCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 6
We are grateful to these distinguished Members of the American College of Cardiology who contributed to this collection: Martha Gulati, MD, MS, FACC (Chair) Christie M. Ballantyne, MD, FACC Anum Saeed, MD Salim S. Virani, MD, FACC Karol E. Watson, MD, FACC
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Mashup Score: 3Exertional Shortness of Breath - American College of Cardiology - 1 year(s) ago
The patient is a 70-year-old male with a history of diabetes mellitus type I, hypertension, hyperlipidemia, anemia, paroxysmal atrial fibrillation, and s/p atrial flutter ablation 6 months ago. He presents with dyspnea on exertion, pedal edema, and weight gain. An electrocardiogram (ECG) (Figure 1) is performed. Figure 1
Source: American College of CardiologyCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
We are grateful to these distinguished Members of the American College of Cardiology who contributed to this collection: Martha Gulati, MD, MS, FACC (Chair) Christie M. Ballantyne, MD, FACC Anum Saeed, MD Salim S. Virani, MD, FACC Karol E. Watson, MD, FACC
Source: learn.acc.orgCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 1
We are grateful to these distinguished Members of the American College of Cardiology who contributed to this collection: Martha Gulati, MD, MS, FACC (Chair) Christie M. Ballantyne, MD, FACC Anum Saeed, MD Salim S. Virani, MD, FACC Karol E. Watson, MD, FACC
Source: learn.acc.orgCategories: Cardiology News and Journals, Latest HeadlinesTweet
In Chinese patients at high or very high #CVD risk with ⬆️ #cvLipids, #tafolecimab was safe and showed lipid-lowering efficacy. https://t.co/TizJPDW34Q 🎧: https://t.co/Iu9aesyWNr #JACCAsia #cvCAD #Hypercholesterolemia #CardioTwitter #JACCPodcast https://t.co/8JNER67ZRB