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Mashup Score: 13Study finds microRNA can predict severe Crohn's disease in children - 1 month(s) ago
When comparing intestinal samples of children with Crohn’s disease and healthy children, one molecule stands out: the microRNA (miRNA) miR-29, which shows significant differences between the two groups, …
Source: medicalxpress.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 34MSCs mediate long-term efficacy in a Crohn’s disease model by sustained anti-inflammatory macrophage programming via efferocytosis - 3 month(s) ago
npj Regenerative Medicine – MSCs mediate long-term efficacy in a Crohn’s disease model by sustained anti-inflammatory macrophage programming via efferocytosis
Source: www.nature.comCategories: General Medicine News, General HCPsTweet-
New study on promising stem cell-based therapy for #Crohn'sDisease https://t.co/A8w0l4U1xC https://t.co/ENeY3QChm0
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Mashup Score: 19Observational Burden of Illness Study in Patients With Crohn’s Disease With and Without Perianal Fistulas in the United States - 4 month(s) ago
This study compared disease burden, experiences, and health-related quality of life (HRQoL) between patients with Crohn’s perianal fistulas (CPFs) and those with Crohn’s disease (CD) without perianal fistulas (PFs; non-PF CD).
Source: www.ghadvances.orgCategories: General Medicine News, GastroenterologyTweet-
Observational Burden of Illness Study in Patients With #Crohn’s Disease With and Without Perianal Fistulas in the United States ➡️ https://t.co/epk6dETwZr https://t.co/NagHiggVKv
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Mashup Score: 1
DNA methylation alterations may provide important insights into gene-environment interaction in cancer, aging, and complex diseases, such as inflammatory bowel disease (IBD). We aim first to determine whether the circulating DNA methylome in patients requiring surgery may predict Crohn’s disease (CD) recurrence following intestinal resection; and second to compare the circulating methylome seen in patients with established CD with that we had reported in a series of inception cohorts.
Source: www.cmghjournal.orgCategories: Gastroenterology, Latest HeadlinesTweet-
Study examines the circulating DNA methylome in adults with new and established #Crohn’s disease undergoing surgery within a large RCT. Learn more at https://t.co/eJWsrrKZoI https://t.co/yfqOVa5N03
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Mashup Score: 0Gili Focht on a New Tool for Assessing Pediatric Crohn's Disease - 9 month(s) ago
Crohn’s disease (CD) is often more extensive in children compared with adults and requires a tool using magnetic resonance enterography (MRE) for assessing inflammation in the entire bowel. To that end, Gili Focht, MSc, MBA, of the Juliet Keidan Institute of Pediatric Gastroenterology, Hepatology, and Nutrition at the Hebrew University of Jerusalem, and an international team of researchers developed and validated the Pediatric Inflammatory Crohn’s Magnetic Resonance Enterography Index (PICMI), which evaluates transmural inflammation in all segments of the intestine and without the use of rectal contrast agents.
Source: www.medpagetoday.comCategories: General Medicine News, Latest HeadlinesTweet-
ICYMI: How did it differ from previous imaging methodologies for childhood #Crohn’s Disease? #AGAReadingRoom @AmerGastroAssn #Gastroenterology Read more: https://t.co/phzNhyBipg https://t.co/OnzuTXvdsm
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Mashup Score: 0More than 60% of Crohn’s patients sustained remission with subcutaneous biosimilar CT-P13 - 11 month(s) ago
CHICAGO — Subcutaneous maintenance therapy with an infliximab biosimilar after IV induction resulted in sustained clinical remission and greater endoscopic response vs. placebo in patients with moderate to severe Crohn’s disease. “In the past several years, there have been a number of formulations of infliximab that have met criteria for what is known as biosimilarity,”
Source: www.healio.comCategories: Gastroenterology, Latest HeadlinesTweet-
According to @NMH_SHanauerMD, more than 60% of #Crohn’ patients sustained remission with subcutaneous biosimilar CT-P13 #DDW23 #GITwitter https://t.co/SYpUQSAKf5
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Mashup Score: 0Maia Kayal on Reappraising Trials Assessing Biologics for Crohn's - 12 month(s) ago
Promising induction responses do not translate into good 1-year net clinical remission rates
Source: www.medpagetoday.comCategories: General Medicine News, Latest HeadlinesTweet-
ICYMI: What were the main findings and did any of the trials analyzed in particular show a gap between response and net #remission? #Crohn’s #AGAReadingRoom @AmerGastroAssn #Gastroenterology Read more: https://t.co/2MAh0SfAjr https://t.co/X9nZKacmWQ
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Mashup Score: 3
Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis.
Source: EurekAlert!Categories: General Medicine News, Latest HeadlinesTweet-
Fresh insights into how our bodies interact with the #microbes living in our #guts suggest that a two-drug combination may offer a new way to treat #inflammatory #bowel #diseases such as #Crohn’s disease and ulcerative colitis @CincyChildrens https://t.co/jArhSB2C0L
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Mashup Score: 0
Clinical and endoscopic healing did not lower the risk of disease progression
Source: www.medpagetoday.comCategories: General Medicine News, Latest HeadlinesTweet-
ICYMI: What was the impetus for this follow-up analysis? #Crohn’s #AGAReadingRoom @AmerGastroAssn #Gastroenterology Read more: https://t.co/bOZY7QmMaT https://t.co/HAaUuBOpfM
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Mashup Score: 3Th17 Cell-Derived Amphiregulin Promotes Colitis-Associated Intestinal Fibrosis Through Activation of mTOR and MEK in Intestinal Myofibroblasts - 1 year(s) ago
Th17 cells induce more severe intestinal fibrosis through the production of Areg, which promotes human intestinal myofibroblast proliferation and migration. Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet-
Findings reveal that Th17-derived amphiregulin promotes intestinal fibrotic responses in experimental #colitis and human patients with #Crohn’s disease. Learn more at: https://t.co/1M7FjVMkuT https://t.co/H1asZ1CBxy
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Study finds microRNA can predict severe #Crohn'sDisease in children @cornell https://t.co/f3CaxzOwfe