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    Patients with germline SDHD pathogenic variants (encoding succinate dehydrogenase subunit D; ie, paraganglioma 1 syndrome) are predominantly affected by head and neck paragangliomas, which, in almost 20% of patients, might coexist with paragangliomas arising from other locations (eg, adrenal medulla, para-aortic, cardiac or thoracic, and pelvic). Given the higher risk of tumour multifocality and bilaterality for phaeochromocytomas and paragangliomas (PPGLs) because of SDHD pathogenic variants than for their sporadic and other genotypic counterparts, the management of patients with SDHD PPGLs is clinically complex in terms of imaging, treatment, and management options.

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    • #Clinical #consensus #guideline on the management of #phaeochromocytoma and #paraganglioma in patients harbouring germline SDHD pathogenic variants https://t.co/PJSiZnUXga #PPGLs #FREE to read with registration (also FREE) https://t.co/Ft03vxQZwd

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    More than 20 years after having been initially proposed, the relevance and usefulness of basophil activation test (BAT) for the field of allergy research and testing were demonstrated on many occasions. Leveraging the fully open format of a flexible, whole blood–based functional assay, BAT has been shown to be equally important for fundamental research, clinical research, and diagnosis. Regardless of whether the focus of a study is on the characterization of the allergenic moiety, on the patient side, or on the study of the fundamental processes involved in the allergic disease or its treatment, BAT enables the gathering of very important insights.

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    • In Current Issue! Promises and Remaining #Challenges for Further Integration of #Basophil #Activation #Test in #Allergy-Related #Research and #Clinical #Practice https://t.co/e9jYSEwrNN https://t.co/10nzF0Hitj

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    Learn how to help maintain healthspan for people with human immunodeficiency virus (HIV).

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    • ⏰ We have a #clinical question for you! #IDWeek2023 Long-term use of tenofovir alafenamide (TAF) is linked to an increased risk of which condition? #HIV Want to learn more? Take our free #CME here: https://t.co/KKBfRkJfAa

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    October 11, 2023 — Realizing a vision to deliver the best care to patients close to where they live in northern Ohio, GE HealthCare and University Hospitals (UH) announced a 10-year strategic collaboration to bring GE HealthCare technologies to UH across its radiology practice and UH Harrington Heart & Vascular Institute, providing contemporary equipment and digital solutions to improve processes for the benefit of patients and clinicians. The agreement includes hundreds of new systems, including AI-enabled technologies, across nuclear medicine, X-Ray, vascular and cardiovascular ultrasound, regional CT, fluoroscopy, surgery, and bone densitometry for which GE HealthCare will be the sole provider. A focus of the collaboration is to implement enterprise-wide technology to optimize workflows and help improve clinical decision-making. “Driven by a mission to heal, to teach, and to discover, University Hospitals offers access to quality care for everyone in Northeast Ohio,” says UH Chief O

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    • @DAICeditor @GEHealthCare #Technology-powered collaboration aims to deliver #AI-enabled devices and digital solutions at the enterprise level to increase #clinical and operational #efficiencies, drive #workflow enhancements and improve patient #outcomes: https://t.co/I6gOgEqXPs

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    Author links open overlay panel Ankita Agarwal MD, MSc a, Joseph Marion PhD b, Paul Nagy PhD c d, Matthew Robinson MD e, Allan Walkey MD, MSc f, Jonathan Sevransky MD, MHS a • Current challenges to interventional trials and critical care research include an inefficient trial design, heterogenous patient populations, heterogeneous treatment effects, and difficulties with patient enrollment. • Precise phenotyping of critically ill patients may allow more targeted enrollment of patients in critical care

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    Severe asthma affects about 10% of the population with asthma and is characterized by low lung function and a high count of blood leukocytes, mainly eosinophils. Various definitions are used in clinical practice and in the literature to identify asthma remission: clinical remission, inflammatory remission, and complete remission. This work highlights a consensus for asthma remission using a Delphi method. In the context of the Severe Asthma Network Italy, which accounts for 57 severe asthma centers and more than 2,200 patients, a board of six experts drafted a list of candidate statements in a questionnaire, which has been revised to minimize redundancies and ensure clear and consistent wording for the first round (R1) of the analysis.

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    • In Press! SANI definition of #Clinical #Remission in #Severe #Asthma: a Delphi consensus https://t.co/NI0qAxLVff