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    Immune checkpoint inhibitors such as anti-PD-1 receptor antibodies have been shown to be effective in patients with advanced gastric cancer. However, there is a growing concern about immune-related adverse events. A case of a patient with gastric adenocarcinoma who developed toxic epidermal necrolysis (TEN) induced by sintilimab and subsequently developed lichenoid dermatitis is reported. TEN was diagnosed according to a history of sintilimab use, clinical symptoms and physical examination. During hospitalization, the patient developed recurrent fever caused by bacteremia and recovered from TEN after anti-infection and anti-inflammatory treatments. However, when TEN was controlled, the patient developed the lesional manifestations of lichenoid dermatitis. To date, no cases of lichenoid dermatitis after TEN have been reported following the use of PD-1 inhibitors.

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    • PD-1 inhibitors fight stomach cancer but can cause skin problems, from minor to severe like toxic epidermal necrolysis. A unique case reports a rare combo: lichenoid dermatitis after TEN due to PD-1 treatment #CaseReport #GastricAdenocarcinom https://t.co/RA9KZmPb7j

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    This cardiology case report from Brady Pregerson, MD, features man in his late-60s presenting to urgent care with 3 days of upper respiratory infection symptoms and one episode of near syncope. Check out the ECG and see if you can determine the correct diagnosis!

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    • Check out the latest cardiology #CaseReport from Dr. Pregerson. https://t.co/Tw7f6vgS1e #Cardiology https://t.co/FDP6VdMnjC