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Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a hematologic malignancy associated with overexpression of CD123. Allogeneic chimeric antigen...

Key Points. Race, ethnicity, and body-mass index did not impact CAR T-cell efficacy or neurotoxicity outcomesHispanic patients were more likely to experience...

Vitamin D insufficiency is a potentially modifiable risk factor for poor outcomes in newly diagnosed large B-cell lymphoma (LBCL). However, the role...

Key Points. Currently, patients receive a single dose of tisagenlecleucel across a wide dose range.Clinicians would choose to give a higher dose of...

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About ScienceDirectRemote accessShopping cartAdvertiseContact and supportTerms and conditionsPrivacy policyWe use cookies to help provide and enhance our service and tailor content and ads. By...

Tyler Routh is one of 13 leukemia patients who had a remarkable recovery after participating in Dr. Samer Khaled’s CAR T trial at City...

Research on CAR T-cell therapy is progressing rapidly to improve the cancer treatment, expand its use to more cancers, and better manage its side...

Chimeric antigen receptor (CAR)-T cell therapy is a progressive new pillar in immune cell therapy for cancer. It has yielded remarkable clinical responses in...

Yi Lin, MD, PhD, Mayo Clinic, Rochester, MN, discusses advances in allogeneic CAR-T therapy for the treatment of relapsed/refractory...