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    Among 20 leading global risk factors for years of life lost in 2040, reference forecasts point to three metabolic risks—high blood pressure, high BMI, and high fasting plasma glucose—as being the top risk variables. Building upon these and other risk factors, the concept of metabolic health is attracting much attention in the scientific community. It focuses on the aggregation of important risk factors, which allows the identification of subphenotypes, such as people with metabolically unhealthy normal weight or metabolically healthy obesity, who strongly differ in their risk of cardiometabolic diseases.

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    • #Metabolic health and #cardiometabolic risk #clusters: implications for prediction, prevention, and treatment https://t.co/Q5NFbaZ4Bj #obesity #diabetes https://t.co/pTmTO1o2nn

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    Menopause is often a turning point for women’s health worldwide. Increasing knowledge from experimental data and clinical studies indicates that cardiometabolic changes can manifest at the menopausal transition, superimposing the effect of ageing onto the risk of cardiovascular disease. The menopausal transition is associated with an increase in fat mass (predominantly in the truncal region), an increase in insulin resistance, dyslipidaemia, and endothelial dysfunction. Exposure to endogenous oestrogen during the reproductive years provides women with protection against cardiovascular disease, which is lost around 10 years after the onset of menopause.

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    • Increasing knowledge from experimental data and clinical studies indicates that #cardiometabolic changes can manifest at the #menopausal transition, superimposing the effect of #ageing onto the risk of cardiovascular disease https://t.co/522BQSaIxS #Menopause #WomensHealth #CVD

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    Incomplete understanding of the multiple mechanisms underlying the link between ultra-processed foods and cardiometabolic health should not be an excuse for inaction argue Mathilde Touvier and colleagues The effect of diet on health has historically been considered from a nutrient based perspective—for example, excess total fat, saturated fat, dietary cholesterol, calories, sugar, or salt and lack of dietary fibre, vitamins, and minerals.1 More recently, this approach has been complemented by extensive evidence supporting health effects of dietary patterns (eg, the Mediterranean diet), characterised by various dietary scores such as the Alternative Healthy Eating Index (AHEI), or DASH (Dietary Approaches to Stop Hypertension) diet.2 However, the degree of processing and formulation of foods was not taken into account. For instance, all vegetable soups were considered similar, regardless of whether they were homemade, industrial canned, or industrial dehydrated and contained food additi

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    • Shortcomings in the evidence base around #ultraprocessed #food and #cardiometabolic health isn't an excuse for inaction. @CRESS_U1153 & co say we know enough to justify #publichealth response to reduce individual consumption. 👉Read more: https://t.co/xxdG2CfoHF @BernardSrour