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Mashup Score: 0
Objective Poor medication adherence remains highly prevalent and adversely affects health outcomes. Patients frequently describe properties of the pills themselves, like size and shape, as barriers, but this has not been evaluated objectively. We sought to determine the extent to which oral medication properties thought to be influential translate into lower objectively-measured adherence. Design Retrospective cohort study. Setting US nationwide commercial claims database, 2016–2019. Participants Among patients initiating first-line hypertension, diabetes or hyperlipidaemia treatment based on clinical guidelines, we measured pill size, shape, colour and flavouring, number of pills/day and fixed-dose combination status as properties. Outcome measures Outcomes included discontinuation after the first fill (ie, never filling again over a minimum of 1-year follow-up) and long-term non-adherence (1-year proportion of days covered <0.80). We estimated associations between each property and o
Source: bmjopen.bmj.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 1Food for Thought 2023 - 6 month(s) ago
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Source: www.bmj.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 4Metabolic health and cardiometabolic risk clusters: implications for prediction, prevention, and treatment - 6 month(s) ago
Among 20 leading global risk factors for years of life lost in 2040, reference forecasts point to three metabolic risks—high blood pressure, high BMI, and high fasting plasma glucose—as being the top risk variables. Building upon these and other risk factors, the concept of metabolic health is attracting much attention in the scientific community. It focuses on the aggregation of important risk factors, which allows the identification of subphenotypes, such as people with metabolically unhealthy normal weight or metabolically healthy obesity, who strongly differ in their risk of cardiometabolic diseases.
Source: www.thelancet.comCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 0Menopause: a cardiometabolic transition - 6 month(s) ago
Menopause is often a turning point for women’s health worldwide. Increasing knowledge from experimental data and clinical studies indicates that cardiometabolic changes can manifest at the menopausal transition, superimposing the effect of ageing onto the risk of cardiovascular disease. The menopausal transition is associated with an increase in fat mass (predominantly in the truncal region), an increase in insulin resistance, dyslipidaemia, and endothelial dysfunction. Exposure to endogenous oestrogen during the reproductive years provides women with protection against cardiovascular disease, which is lost around 10 years after the onset of menopause.
Source: www.thelancet.comCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 1Food for Thought 2023 - 6 month(s) ago
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Source: www.bmj.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 0Food for Thought 2023 - 7 month(s) ago
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Source: www.bmj.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 9Prevention&Intervention | Prevention&Intervention - 7 month(s) ago
Prevention&Intervention – when preventive cardiology meets interventional cardiology
Source: prev-interv.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0Ultra-processed foods and cardiometabolic health: public health policies to reduce consumption cannot wait - 7 month(s) ago
Incomplete understanding of the multiple mechanisms underlying the link between ultra-processed foods and cardiometabolic health should not be an excuse for inaction argue Mathilde Touvier and colleagues The effect of diet on health has historically been considered from a nutrient based perspective—for example, excess total fat, saturated fat, dietary cholesterol, calories, sugar, or salt and lack of dietary fibre, vitamins, and minerals.1 More recently, this approach has been complemented by extensive evidence supporting health effects of dietary patterns (eg, the Mediterranean diet), characterised by various dietary scores such as the Alternative Healthy Eating Index (AHEI), or DASH (Dietary Approaches to Stop Hypertension) diet.2 However, the degree of processing and formulation of foods was not taken into account. For instance, all vegetable soups were considered similar, regardless of whether they were homemade, industrial canned, or industrial dehydrated and contained food additi
Source: www.bmj.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 1Food for Thought 2023 - 7 month(s) ago
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Source: www.bmj.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 2Food for Thought 2023 - 7 month(s) ago
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Source: www.bmj.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
🔎 Investigating the ability to adhere to #cardiometabolic medications with different properties: a retrospective cohort study of >500,000 patients in the USA 👉 https://t.co/UD2uifOiU9 https://t.co/SdRFvCR5KE