• Mashup Score: 36

    Immune-related adverse events, particularly severe toxicities such as myocarditis, are major challenges to the utility of immune checkpoint inhibitors (ICIs) in anticancer therapy1. The pathogenesis of ICI-associated myocarditis (ICI-MC) is poorly understood. Pdcd1–/–Ctla4+/– mice recapitulate clinicopathological features of ICI-MC, including myocardial T cell infiltration2. Here, using…

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    • Our story in @Nature is testament 2 A+ #CardioOnc team effort. Excited about translating these findings 2 help our patients. Join our ICI-myocarditis registry & our team! At @UCSFCardiology also excited 2 contribute 2 the new field of #CardioImmunology! https://t.co/l8KVqgqSSl https://t.co/FXsiHa70nw

  • Mashup Score: 8

    Cardioimmunology is a field that encompasses the immune cells and pathways that modulate cardiac function in homeostasis and regulate the temporal balance between tissue injury and repair in disease. Over the past two decades, genetic fate mapping and high-dimensional sequencing techniques have defined increasing functional heterogeneity of innate and adaptive immune cell populations in the heart…

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    • New Review! @EpelmanLab @AnthonyWongUofT & @Homaira_H summarize the latest advances in #cardioimmunology and use case-based examples to explain new tools and concepts in #immunology and provide recommendations for studying immune cells in cardiac disease https://t.co/ST7Jueboky https://t.co/xynIqRGvAy

  • Mashup Score: 1

    The UCSF Section of Cardio-Oncology and Immunology brings together clinical cardiologists, oncologists, immunologists, together with basic, translational, and clinical researchers to work collaboratively in order to promote and optimize the cardiovascular health of cancer patients.

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    • At @UCSFCardiology we are placing a special focus on #CardioOncoMetabolism! Special interest in how metabolic perturbations of new cancer therapies can teach use about cardiac metabolism as well as metabolic drivers of #CardioImmunology! https://t.co/8XBT4CprE4

  • Mashup Score: 0

    Highlights • NETs have been implicated as therapeutic targets to address inflammation and thrombotic tissue damage in conditions such as sepsis, acute respiratory disease syndrome, COVID-19, and CV…

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    • How does hydrogen gas affect #neutrophil extracellular traps (NETs), and could it be a novel therapeutic strategy for diseases involving NETs? Learn more in this issue of #JACCBTS: https://t.co/H75YJl7Yvy #CardioImmunology #openaccess #BasicScience #TranslationalScience https://t.co/Ta86126Oqp

  • Mashup Score: 2

    AbstractAims. Hypertension is the major cause of cardiovascular diseases and global mortality. Immunoglobulin E (IgE), which plays crucial roles in allergic dis

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    • New #CardiovascularResearch study finds IgE activation of #MastCells causes #EndothelialCell dysfunction & drives pathogenesis of #hypertension Is IgE a new therapeutic 🎯 for ⬆️#BloodPressure? https://t.co/ZkLur4lOQI @CVR_TomaszGuzik @DrMikeDrozd @glenpyle #cardioimmunology https://t.co/K32YReoT1c

  • Mashup Score: 22
    Javid Moslehi, MD - 2 year(s) ago

    Research Overview: An overarching theme of the Moslehi laboratory is to better understand cardiovascular signaling, especially in response to various stressors including inflammation, aging, and hypoxia. The Moslehi laboratory is closely integrated with the newly formed Section of Cardio-Oncology and Immunology at UCSF, leveraging novel clinical observations into fundamental basic questions that…

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    • Glad to officially join @UCSF Biomedical Sciences Graduate Program (BMS). Our laboratory is leveraging #CardioOnc & #CardioImmunology as platforms for CV investigation and interested in cardiovascular signaling. Excited 2B at @UCSFCardiology @UCSFCancer! https://t.co/x2q997lm58 https://t.co/u2ScTKCHoN