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    Summary:. By shedding light on the cellular origins of circulating DNA (cirDNA), this research provides important insights into the mechanisms of cirDNA production in cancer. Contrary to expectations, the increased cirDNA in patients with cancer was not derived predominantly from neoplastic cells or surrounding nonneoplastic epithelial cells; rather, the excess cirDNA originated primarily from leukocytes, implying a systemic impact of cancer on cell turnover or DNA clearance.See related article by Mattox et al., p. 2166 (1).

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    • In the Spotlight— A new paradigm of the origins of circulating DNA in #cancerpatients, by @artart77529476 and Ekaterina Pisareva. https://t.co/gOsszRkr1n @Inserm #LiquidBiopsy https://t.co/GzqwrD4jAO

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    In the MATCH-R study, comprehensive profiling included successful sequencing of DNA and of RNA, enabling detection of actionable genomic alterations

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    • #MAP2023: Complete molecular characterisation is feasible in many #CancerPatients. In the MATCH-R study, comprehensive profiling included successful sequencing of DNA and also of RNA, enabling the detection of actionable genomic alterations. 👉https://t.co/Qvx6E3uhg8 https://t.co/v4nXmrG8y6

  • Mashup Score: 1
    article - 7 month(s) ago

    NewsOncology Times45(8):p 17-18, April 20, 2023. | DOI: 10.1097/01.COT.0000932012.82499.42Next-Generation Cell TherapiesNext-Generation Cell TherapiesThe Friends of Cancer Research (Friends) held a webinar to update progress on its project aimed at accelerating the development of engineered cell therapies for cancer patients. Jeff Allen, PhD, President and CEO of Friends, said the organization…

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    • The Friends of Cancer Research (Friends) held a webinar to update progress on its project aimed at accelerating the development of engineered cell therapies for #cancerpatients. Read it here: https://t.co/OFbxbvJBFI #CancerResearch https://t.co/LDzj0m55nU

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    This handout discusses potential benefits and risks of learning your test results online. You’ll find tips for managing your expectations and minimizing stress. During and after cancer treatment, a common greeting—How are you? —may stir unpleasant emotions or cause confusion about how to answer. This handout offers insights and tips on responding in ways that help you. The key message is this: In medical settings, answering candidly is essential to optimizing your care. You may experience treatment

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    • Oncology social workers can make a great impact on the lives of #cancerpatients. This patient handout can be your tool in helping patients understand the positive impact a #socialworker can have on their life. Access the handout here: https://t.co/qUohhRD2P3 https://t.co/acLJ26Z5Ax