• Mashup Score: 2

    Objective To comprehensively examine the associations between changes in carbohydrate intake and weight change at four year intervals. Design Prospective cohort study. Setting Nurses’ Health Study (1986-2010), Nurses’ Health Study II (1991-2015), and Health Professionals Follow-Up Study (1986-2014). Participants 136 432 men and women aged 65 years or younger and free of diabetes, cancer, cardiovascular disease, respiratory disease, neurodegenerative disorders, gastric conditions, chronic kidney disease, and systemic lupus erythematosus before baseline. Main outcome measure Weight change within a four year period. Results The final analyses included 46 722 women in the Nurses’ Health Study, 67 186 women in the Nurses’ Health Study II, and 22 524 men in the Health Professionals Follow-up Study. On average, participants gained 1.5 kg (5th to 95th centile −6.8 to 10.0) every four years, amounting to 8.8 kg on average over 24 years. Among men and women, increases in glycemic index and glyce

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    • Swapping starch and refined carbs for whole grains and fruit is linked to less midlife weight gain, finds study. Includes a visual abstract #BMJInfographic summarising the findings https://t.co/kiFtg7EYYp https://t.co/9lNJYrhlqP

  • Mashup Score: 6

    Lung conditions are the third biggest killer in the UK, yet The BMJ finds a postcode lottery for access to crucial diagnostic services that most impacts the areas with the highest burden. Sally Howard reports The BMJ has found that patients in some of the most deprived areas of the UK, where respiratory conditions including chronic obstructive pulmonary disease (COPD) and asthma are twice as prevalent,1 have limited or no access to crucial respiratory diagnostics. GPs in some of the worst affected areas say the fact they have no means of referring patients for tests, including spirometry and fractional exhaled nitric oxide (FeNO) analysis, is “troubling” and “a silent scandal”—despite NHS England trumpeting its rollout of “one stop shop” community diagnostic centres (CDCs),2 some of which will be run by private providers.3 London GP (and BMJ columnist) Rammya Mathew says COPD is a “known disease of deprivation and a key focus of Core20PLUS5”—the NHS England initiative launched in 2021

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    • Patients in some of the most deprived areas of England, where respiratory conditions are most prevalent, have limited or no access to vital tests, reveals survey by The BMJ. Use our interactive map to see your area's availability #BMJInfographic https://t.co/xL29A9SIz7 https://t.co/23ZSTR7ssq

  • Mashup Score: 23

    Objective To systematically review the proportions of infants with early exposure to antenatal corticosteroids but born at term or late preterm, and short term and long term outcomes. Design Systematic review and meta-analyses. Data sources Eight databases searched from 1 January 2000 to 1 February 2023, reflecting recent perinatal care, and references of screened articles. Eligibility criteria for selecting studies Randomised controlled trials and population based cohort studies with data on infants with early exposure to antenatal corticosteroids (<34 weeks) but born at term (≥37 weeks), late preterm (34-36 weeks), or term/late preterm combined. Data extraction and synthesis Two reviewers independently screened titles, abstracts, and full text articles and assessed risk of bias (Cochrane risk of bias tool for randomised controlled trials and Newcastle-Ottawa scale for population based studies). Reviewers extracted data on populations, exposure to antenatal corticosteroids, and outcom

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    • Study finds about 40% of infants exposed to early antenatal corticosteroids were born at term, with associated adverse outcomes, highlighting the need for caution when considering antenatal corticosteroids. Includes a visual abstract #BMJInfographic https://t.co/26HxkKEyDJ https://t.co/N59PQd34FS