• Mashup Score: 0

    Associate Editors Hendrickson and Ortel edited a How I Treat series on inpatient consultative hematology. In this timely series of articles, the authors present

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    • How I approach #bleeding in hospitalized patients #ConsultativeHematology -> an essential series! 👉https://t.co/cEPmAtWNI9 @BloodJournal @Bsamuelson_md https://t.co/QYaTafemV1

  • Mashup Score: 2

    In the STOPDAPT-3 trial, an aspirin-free strategy after PCI did not reduce major bleeding event risk compared with dual antiplatelet therapy, with data also suggesting a signal for excess coronary events, a speaker reported. DAPT with a P2Y12 inhibitor on top of aspirin therapy is the established treatment to prevent ischemic CV events, in particular stent thrombosis, at least 1 month after PCI;

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    • The STOPDAPT-3 trial found that an #aspirin-free strategy following #PCI failed to reduce major #bleeding risk vs. dual #antiplatelet therapy. https://t.co/yaXZZAvQj5

  • Mashup Score: 9

    Coronary artery disease (CAD) is highly prevalent in older adults, yet its management remains challenging. Treatment choices are made complex by the frailty burden of older patients, a high prevalence of comorbidities and body composition abnormalities (e.g., sarcopenia), the complexity of coronary anatomy, and the frequent presence of multivessel disease, as well as the coexistence of major ischemic and bleeding risk factors. Recent randomized clinical trials and epidemiological studies have provided new data on optimal management of complex patients with CAD. However, frail older adults are still underrepresented in the literature. This narrative review aims to highlight the importance of assessing frailty as an aid to guide therapeutic decision-making and tailor CAD management to the specific needs of older adults, taking into account age-related pharmacokinetic and pharmacodynamic changes, polypharmacy, and potential drug interactions. We also discuss gaps in the evidence and offer

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    • JCM | Free Full-Text | Management of Coronary Artery Disease in Older Adults: Recent Advances and Gaps in Evidence. #ACS #Frailty #Teamwork #CAD #OMT #bleeding #SSP https://t.co/tWaikQOOhL

  • Mashup Score: 7

    This editorial refers to ‘Effectiveness of aortic valve replacement in Heyde syndrome: a meta-analysis’, by L.C.M.J. Golstein et al., https://doi.org/10.1093/eu

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    • Heyde syndrome: could aortic valve replacement resolve gastrointestinal bleeding? Read more on #EHJ #aortic #stenosis #gastrointestinal #bleeding @ESC_Journals @escardio #cardiotwitter #EHJ @MoritzSeiffert https://t.co/AFmPyWP1sP https://t.co/leyYMmBdtS