biomolecules – MashupMD

Mashup Score: 3

Stabilization Effect of Intrinsically Disordered Regions on Multidomain Proteins: The Case of the Methyl-CpG Protein 2, MeCP2 - 3 year(s) ago

Intrinsic disorder plays an important functional role in proteins. Disordered regions are linked to posttranslational modifications, conformational switching, extra/intracellular trafficking, and allosteric control, among other phenomena. Disorder provides proteins with enhanced plasticity, resulting in a dynamic protein conformational/functional landscape, with well-structured and disordered…

Source: MDPI

Categories: Future of Medicine, Latest Headlines

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- ManelEsteller
  
  Helping #Rettsyndrome research by studying features of the MeCP2 protein, mutated in the disease, collaboration lead by Adrian Velazquez-Campoy #BFI @unizar @CSIC in #Biomolecules https://t.co/rkkuWGko8V via @MDPIOpenAccess

Mashup Score: 0

Personalized regenerative medicine company developing implanted cell pouches to treat chronic disease - MedCity News - 3 year(s) ago

In response to emailed questions, Encellin CEO offered an overview of the company’s device that functions like a pouch to help implanted cells survive in the body.

Source: MedCity News

Categories: Future of Medicine, Latest Headlines

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- PulmonaryApps
  
  Encellin has invented a soft cell encapsulation device that allows enclosed cells to function like smart molecular factories, releasing therapeutics when needed via @medcitynews https://t.co/beHQcoPmRG #implants #biomolecules #CED #krystalklear #pulmonaryapps https://t.co/rzToN43BaQ

Mashup Score: 2

Large-scale Multi-omic Analysis of COVID-19 Severity - 4 year(s) ago

Leukocyte mRNA expression and plasma protein, metabolite, and lipid levels were measured in 102 COVID-19 and 26 non-COVID patient samples. 219 diverse biomolecules were strongly associated with COVID-19 status and severity and pointed to dysregulation of processes related to lipid transport, blood coagulation, acute phase response, endotheliopathy, and neutrophil degranulation in this disease.

Source: Cell Systems

Categories: General Medicine News, Latest Headlines

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- CellPressNews
  
  Multi-omic analysis of #COVID19 identifies 219 #biomolecules strongly associated with #disease status and severity. Read more in @CellSystemsCP https://t.co/1gAxh3Ui71 https://t.co/WNKjIjKW7J