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Mashup Score: 0Conferences | Keystone Symposia - 1 year(s) ago
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Source: www.keystonesymposia.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 1Voices of the new generation: establishing yourself as a PI in a competitive field - Nature Reviews Molecular Cell Biology - 3 year(s) ago
Jonathon Ditlev shares his thoughts on building a research programme in a competitive field.
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Mashup Score: 6Volume 22 Issue 10, October 2021 - 3 year(s) ago
Volume 22 Issue 10, October 2021
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Mashup Score: 31Nuclear compartmentalization as a mechanism of quantitative control of gene expression - Nature Reviews Molecular Cell Biology - 3 year(s) ago
An emerging model of gene regulation posits that DNA, RNA and proteins form condensate nuclear compartments that facilitate cooperative interactions. This Review discusses how compartmentalization can lead to non-stoichiometric molecular interactions and behaviours in transcription, co-transcriptional and post-transcriptional RNA processing, and higher-order chromatin regulation.
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Mashup Score: 16Nuclear compartmentalization as a mechanism of quantitative control of gene expression - Nature Reviews Molecular Cell Biology - 3 year(s) ago
An emerging model of gene regulation posits that DNA, RNA and proteins form condensate nuclear compartments that facilitate cooperative interactions. This Review discusses how compartmentalization can lead to non-stoichiometric molecular interactions and behaviours in transcription, co-transcriptional and post-transcriptional RNA processing, and higher-order chromatin regulation.
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Mashup Score: 0Phase separation in biology - 3 year(s) ago
A collection of Reviews from Nature Reviews Molecular Cell Biology, and research papers from the Nature journals, on phase separation mechanisms and the roles of biomolecular condensates.
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Mashup Score: 7Voices of the new generation: establishing yourself as a PI in a competitive field - Nature Reviews Molecular Cell Biology - 3 year(s) ago
Jonathon Ditlev shares his thoughts on building a research programme in a competitive field.
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Mashup Score: 2Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing - 3 year(s) ago
Biomolecular condensates, which form via liquid−liquid phase separation in a tightly regulated manner, have fundamental roles in cellular organization and physiology. Recent studies provide insight into how cellular stress, ageing-related loss of homeostasis and a decline in protein quality control may contribute to the formation of aberrant, disease-causing condensates.
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Mashup Score: 1
Recent studies have highlighted the contribution of RNA to cellular liquid–liquid phase separation and condensate formation. RNA features modulate the composition and biophysical properties of RNA–protein condensates, which have various cellular functions, including RNA transport and localization, supporting catalytic processes and responding to stress.
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Mashup Score: 0A framework for understanding the functions of biomolecular condensates across scales - 3 year(s) ago
Biomolecular condensates are membraneless molecular assemblies formed via liquid–liquid phase separation. They have a plethora of roles, ranging from controlling biochemical reactions to regulating cell organization and cell function. This article provides a framework for the study of condensate functions across these cellular length scales, offering to bring new understanding of biological…
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We'll join the @KeystoneSymp on #BiomolecularCondensates, January 29-1, 2023, Vancouver, Canada. 👉🏽 Register NOW: https://t.co/CTOfe8QFw6 #KSBioCondensates23 https://t.co/Hc5Vp662Qd