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Mashup Score: 0The Safety of the Direct Drug Provocation Test in Beta-Lactam Hypersensitivity in Children: A Systematic Review and Meta-Analysis - 1 year(s) ago
Direct drug provocation test (DPT) without prior skin testing (ST) has been investigated in children suspected of being at risk for beta-lactam (BL) hypersensitivity reaction (HSR). However, no systematic review and meta-analysis has investigated the efficacy and safety of direct DPT for BL-HSR in children.
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0The safety of the direct drug provocation test in beta lactam hypersensitivity in children: A systematic review and meta-analysis - 1 year(s) ago
Direct drug provocation test (DPT) without prior skin testing (ST) has been investigated in children suspected of being at risk for beta-lactam hypersensitivity reaction (BL-HSR). However, no systematic review and meta-analysis has investigated the efficacy and safety of direct DPT for BL-HSR in children.
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Genetic Engineering of Immune Evasive Stem Cell-Derived Islets - 1 year(s) ago
Genome editing has the potential to revolutionize many investigative and therapeutic strategies in biology and medicine. In the field of regenerative medicine, one of the leading applications of genome engineering technology is the generation of immune evasive pluripotent stem cell-derived somatic cells for transplantation. In particular, as more functional and therapeutically relevant human…
Source: FrontiersCategories: Latest Headlines, TransplantationTweet
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Mashup Score: 6Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine - Nature Communications - 2 year(s) ago
The authors have previously demonstrated the neutralising capacity of their nanoparticle vaccine, as well as showing protection of non-human primates from SARS-CoV-2 WA-1 infection. In this work, they investigate the ability of their vaccine candidate to neutralise SARS-CoV-2 variants of concern, and protect animals from other sarbecoviruses.
Source: NatureCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 0
Since 2019 the Global Initiative on Asthma (GINA) guidelines have explicitly recommended against the use of monotherapy with short-acting β-agonists (SABA) and altogether deleted the term “intermittent asthma” from the severity classification, based on the observations that severe exacerbations and even death can also occur in patients classified as having intermittent asthma and treated with…
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 3Short-Acting Beta-2-Agonist Exposure and Severe Asthma Exacerbations: SABINA Findings From Europe and North America - 2 year(s) ago
Expert national/global asthma management recommendations raise the issue whether a safe threshold of short-acting beta-2 agonist (SABA) use without concomitant inhaled corticosteroids (ICS) exists.
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 49
Emerging SARS-CoV-2 variants of concern/interest (VOC/VOI) raise questions about effectiveness of neutralizing antibodies derived from infection or vaccination. As the population immunity to SARS-CoV-2 has become more complex due to prior infection and/or vaccination, understanding the antigenic relationship between variants is needed. Here, we have assessed in total 104 blood specimens from…
Source: medRxivCategories: Infectious Disease, Latest HeadlinesTweet-
This is also what we have seen in our study: No matter if your prior infection was #SARSCoV2 in 2020, #Alpha, #Beta, #Gamma or #Delta, protection against #Omicron is poor. Omicron is most likely a new serotype that escapes immunity to earlier infection. https://t.co/C8Wl65mcqc https://t.co/ERIE27qiHE
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Mashup Score: 0Robinhood’s Crypto Wallet to Be Released in Beta Next Month - 2 year(s) ago
Robinhood’s new wallet will support deposit and withdrawal of cryptocurrencies including Bitcoin, Dogecoin, and Ether.
Source: NDTV Gadgets 360Categories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 0
National Institutes of Health, National Heart, Lung, and Blood Institute.
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 2Effectiveness of Beta-Lactam plus Doxycycline for Patients Hospitalized with Community-Acquired Pneumonia - PubMed - 2 year(s) ago
In this retrospective observational cohort study, we found that doxycycline use, as part of guideline-concordant antibiotic therapy, was associated with lower 30- and 90-day mortality than regimens without doxycycline. While this supports the safety and effectiveness of antibiotic regimes that inclu …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
In Current Issue! The #Safety of the Direct #Drug #Provocation Test in #Beta- #Lactam #Hypersensitivity in #Children: A Systematic #Review and Meta- #Analysis https://t.co/rfNh6bxmL3 https://t.co/vUDMCvIGWe