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Mashup Score: 7Clinical Characteristics and Outcomes of Mexican Patients... : JCR: Journal of Clinical Rheumatology - 5 month(s) ago
Mexico City from 2000 to 2020. Demographics, clinical characteristics, laboratory and imaging studies, disease activity, damage, treatment, and outcomes were assessed and compared according to sex and with other international cohorts. Descriptive statistics were used, and differences between groups were evaluated using the χ2 or Mann-Whitney U tests. Results Thirty-eight patients were included, 23 (60%) women and 15 (40%) men; the median age at BS diagnosis was 33 years (range, 24–39 years). The most frequent manifestations at diagnosis were recurrent oral and genital ulcers in 34 (89%) and 29 (76%), respectively, musculoskeletal in 21 (55%), and cutaneous in 15 (39%). The most frequent phenotype was the joint involvement. Treatment comprised prednisone in all, colchicine (24 [63%]), pentoxifylline (12 [32%]), and thalidomide (10 [26%]). During a median follow-up time of 12.5 years (range, 7–23 years), relapses were frequent (97%), severe infections were present in 5 patients (13%), an
Source: journals.lww.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 0Characteristics of Patients With Behçet Disease From the... : JCR: Journal of Clinical Rheumatology - 5 month(s) ago
n in the same country. In this study, we aimed to evaluate the clinical features and disease course of BD using cluster analysis in Van province, Eastern Turkey. Methods This study was carried out in a tertiary referral center in Van province, by reviewing medical records. Seven disease manifestations were included to the cluster analysis as follows: mucocutaneous findings (oral ulcer, genital ulcer, erythema nodosum–like lesions, pseudofolliculitis), uveitis, superficial thrombophlebitis, musculoskeletal involvement, gastrointestinal system involvement, vascular involvement, and parenchymal central nervous system involvement. Results We identified 467 patients. After the exclusion of 6 patients who had missing data and 17 patients who did not live in Van, 444 patients (59.2% male) included into the study. Meeting the International Study Group and the International Criteria for Behçet Disease criteria were 91.6% and 96%, respectively, and 91.3% (n = 379/415) of these patients met both
Source: journals.lww.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 1Aortic Valve Replacement by Subannular Endomyocardial Implantation of Valve Prosthesis in Behçet's Disease - PubMed - 11 month(s) ago
The novel anastomosis technique, “subannular endomyocardial implantation of valve prosthesis (SEIV),” focuses on excluding aortic annular tissue from suture line to avoid vascular inflammation in Behçet’s disease (BD). We aimed to validate that SEIV could prevent prosthetic valve detachment (PVD) af …
Source: PubMedCategories: Cardiac Surgery, Latest HeadlinesTweet
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Mashup Score: 4Vascular Behçet syndrome: from pathogenesis to treatment - Nature Reviews Rheumatology - 1 year(s) ago
In this Review, the authors discuss vascular involvement in Behçet syndrome and how the unusual pathogenesis involving an impaired immune-inflammatory response influences the treatment approach, which differs from that of other vasculitides.
Source: NatureCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0Nature Reviews Rheumatology - Volume 19 Issue 2, February 2023 - 1 year(s) ago
Inspired by the Review on p78.
Source: NatureCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 2Vascular Behçet syndrome: from pathogenesis to treatment - Nature Reviews Rheumatology - 1 year(s) ago
In this Review, the authors discuss vascular involvement in Behçet syndrome and how the unusual pathogenesis involving an impaired immune-inflammatory response influences the treatment approach, which differs from that of other vasculitides.
Source: NatureCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0
Objectives The endoplasmic reticulum aminopeptidase ( ERAP1 ) haplotype Hap10 encodes for a variant allotype of the endoplasmic reticulum (ER)-resident peptide-trimming aminopeptidase ERAP1 with low enzymatic activity. This haplotype recessively confers the highest risk for Behçet’s diseases (BD) currently known, but only in carriers of HLA-B*51 , the classical risk factor for the disease. The…
Source: Annals of the Rheumatic DiseasesCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0Impact of apremilast on quality of life in Behçet’s syndrome: analysis of the phase 3 RELIEF study - 2 year(s) ago
Objective To assess apremilast’s impact on patient quality of life (QoL) in active Behçet’s syndrome and correlations between improvement in patients’ QoL and efficacy measures in the phase 3 RELIEF study. Methods QoL measures included Behçet’s Disease QoL (BDQoL), 36-Item Short-Form Health Survey V.2 (SF-36v2) Physical/Mental Component Summary (PCS/MCS) and eight subscale scores, focusing on…
Source: RMD OpenCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0
PDF | Behçet’s Disease is a chronic, multisystemic, inflammatory disorder characterized by intraocular inflammation, oral and mucosal ulcerations, skin… | Find, read and cite all the research you need on ResearchGate
Source: ResearchGateCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Clinical Manifestations and Diagnosis of Behçet’s Syndrome - 2 year(s) ago
Behçet’s syndrome (BS) was first described by Hulusi Behçet in 1931, as a definite clinical entity, the ‘triple symptom complex’, based on…
Source: European Medical JournalCategories: Latest Headlines, RheumatologyTweet
Clinical Characteristics and Outcomes of Mexican Patients With #Behçet’s Syndrome 👇🏻 Set free this month! https://t.co/KThUnHxPy4