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Mashup Score: 0B cell responses to membrane-presented antigens require the function of the mechanosensitive cation channel Piezo1 - 7 month(s) ago
Mechanosensitive Ca2+ signaling in B cells underlies their preference for membrane-bound over soluble antigens.
Source: www.science.orgCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 3B cell responses to membrane-presented antigens require the function of the mechanosensitive cation channel Piezo1 - 7 month(s) ago
Mechanosensitive Ca2+ signaling in B cells underlies their preference for membrane-bound over soluble antigens.
Source: www.science.orgCategories: Future of Medicine, Latest HeadlinesTweet-
A new study in @SciSignal defines an essential event in how #Bcells are activated in response to membrane-presented antigens—findings that may aid in the design of vaccines that better stimulate the production of antibodies. https://t.co/DoEYYuMQKd https://t.co/lKkglSBMiM
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Mashup Score: 0
Artesunate (ART) is a derivative of artemisinin. Compared with artemisinin, ART has excellent water solubility, high stability and oral bioavailability. In this review, the application of ART in classic autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus and ulcerative colitis is summarized. ART exhibited similar or even better efficacy than other highly effective immunosuppressive agents, such as methotrexate and cyclophosphamide. In addition, ART exerts its pharmacological effects mainly by inhibiting the production of inflammatory factors, reactive oxygen species, autoantibodies and the migration of cells to reduce damage to tissues or organs. Moreover, ART widely affected the NF-κB, PI3K/Akt, JAK/STAT and MAPK pathways to exert pharmacological effects.
Source: www.futuremedicine.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Artesunate exerts its pharmacological effects mainly through #NF-κB, #PI3K/Akt, #JAK/ STAT, #MAPK pathways, and is also widely involved in the regulation of #Tcells, #Bcells, and #macrophages Read our latest review on the role of artesunate online: https://t.co/bItUGxD72S
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Mashup Score: 4Nonbinary Roles for T Follicular Helper Cells and T Follicular Regulatory Cells in the Germinal Center Response - 10 month(s) ago
Abstract. Development of high-affinity Abs in the germinal center (GC) is dependent on a specialized subset of T cells called “T follicular helper” (TFH) cells
Categories: Allergy-Immunology, Latest HeadlinesTweet-
#BriefReview by @IN_trons & #JI_Editor @AlexanderDent6 discussing “Nonbinary Roles for T Follicular Helper Cells and T Follicular Regulatory Cells in the #GerminalCenter Response” #ReadTheJI #Tcells #Bcells #antibodies #immunology @IUMedSchool 👉 https://t.co/MCkv0BCx52 https://t.co/QcuoPCO6VG
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Mashup Score: 5B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma - Nature Communications - 11 month(s) ago
B cells are playing an active role in shaping the tumour immune microenvironment and the anti-tumour immune response in melanomas. Here authors show that intra-tumoral B cells are aberrantly activated and produce antibodies that are potentially autoreactive.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
Study uncovers how #Bcells react to skin cancer @kingscollegelon @NatureComms https://t.co/Vpkryce42G https://t.co/EZiZZExlSz
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Mashup Score: 1The Role of Memory B Cells in Infectious Diseases - 1 year(s) ago
Learn more in this Immunology Feature.
Source: www.stemcell.comCategories: Infectious Disease, Latest HeadlinesTweet-
🎓 Learn about memory #Bcells and their role in infectious diseases by reading this @STEMCELLTech #Immunology Feature that investigates recent advancements in the field. https://t.co/wDGIBEiPOl
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Mashup Score: 2
Key Points. The differentiation of lupus autoantigen-specific B cells relies on glycolysis.These B cells are more glycolytic under Ag-specific than TLR7 stimula
Categories: Allergy-Immunology, Latest HeadlinesTweet-
#JI_TopRead from former #JI_Editor Laurence Morel @UTHealthSA | Antigen-specific #Bcells, but not #Tcells, require #glycolysis during systemic #lupus erythematosus | #ReadTheJI #immunometabolism #autoimmunity 👉 https://t.co/hgnpOSZoeu https://t.co/2CAULZtkO7
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Mashup Score: 0
Key Points. Memory T and B cells are present for long periods with different kinetics.Circulating Tfh cells correlate to the Ab production of B cells.Memory T c
Categories: Allergy-Immunology, Latest HeadlinesTweet-
#AuthorChoice: Dynamics of memory #Tcells and #Bcells before and after the third #BNT162b2 #SARSCoV2 booster in a Japanese cohort | from Setsuko Mise-Omata at Keio University School of Medicine | #ReadTheJI #immunology #omicron #COVID 👉 https://t.co/dBIER3Ut3A https://t.co/77mzhGyDpl
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Mashup Score: 4CD40 Drives Central Nervous System Autoimmune Disease by Inducing Complementary Effector Programs via B Cells and Dendritic Cells - 1 year(s) ago
Key Points. CD40 supports distinct effector programs in B cells and DCs for EAE.CD40 expression on DCs is required for priming pathogenic Th cells.B cell CD40 i
Categories: Allergy-Immunology, Latest HeadlinesTweet-
#AAI_Fellow Richard J. Hodes @NINDSnews @NIHAging | The costimulatory molecule #CD40 drives #CNS #autoimmunity through #Bcells and #DendriticCells by distinct pathways | #ReadTheJI #immunology #EAE #MS 👉 https://t.co/Aq6DzGQQS4 https://t.co/u2L6c2MnrR
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Mashup Score: 1Contribution of B cells to cortical damage in multiple sclerosis - 1 year(s) ago
Bhargava et al. review the role that B cells play in mediating cortical demyelination and neuronal damage. They review evidence linking B cells to cortical inju
Source: OUP AcademicCategories: Healthcare Professionals, Latest HeadlinesTweet-
Contribution of #Bcells to cortical damage in #multiplesclerosis https://t.co/CMtkQMSo8N #CNS #Brain #spinalcord #leptomeninges #inflammation #EBV #greymatter #parenchyma https://t.co/ggKTmGodE0
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A new study in @SciSignal defines an essential event in how #Bcells are activated in response to membrane-presented antigens—findings that may aid in the design of vaccines that better stimulate the production of antibodies. https://t.co/pyaeyxiZAQ https://t.co/TSmLBCswrZ